Flashcards in Herbal Supplements Deck (10):
- inhibits platelet aggregation
- can increase the risk of perioperative bleeding, especially if the patient is taking other anticoagulants or NSAIDs.
- recommended that garlic be discontinued 1 week before surgery due to potential for irreversible inhibition of platelet function.
- Used to assist in sleep
- potentiates benzodiazepine effect
- Abrupt discontinuation can lead to a withdrawal syndrome similar to that associated with chronic benzodiazepine use.
- Suggested that valerian be tapered over several weeks.
- If tapering is not possible, it should not be discontinued until the day before surgery.
Herbal supplements that increase the risk of bleeding:
- Used to treat symptoms associated with BPH
- Has been associated with excessive intraoperative bleeding
- attributed to its anti-inflammatory effects and platelet dysfunction.
St John's Wort
- Used to treat mild to moderate depression.
- Believed to be a MAOi and inhibits the reuptake of monoamines.
- A Cyp2c19 inducer and can prolong effects of anesthesia
- Can prolong the effect of clopidogrel in nonresponders
- Reduces the effect of warfarin and heparin
Associated with excess bleeding. Contains compounds that alter vasoregulation, act as antioxidants, modulate neurotransmitter and receptor activity, and INHIBIT platelet activating factor.
Has been used to treat nausea, but has antiplatelet effects and may cause perioperative bleeding, especially when combined with aspirin or NSAIDs.
An anxiolytic or sedative widely used as a CNS depressant, potentiates the effects of benzos and may prolong effects of anesthesia
Decreases postprandial glucose levels and can cause hypoglycemia, potentially irreversible effect on platelets