Hexokinase vs Glucokinase Flashcards Preview

[Topnotch Biochemistry 2017] > Hexokinase vs Glucokinase > Flashcards

Flashcards in Hexokinase vs Glucokinase Deck (10)
Loading flashcards...
1
Q

Has a considerably higher Km (lower affinity) for glucose

A

Glucokinase

2
Q

Present in most tissue

A

Hexokinase

3
Q

Its activity increases with increases in the concentration of glucose in the hepatic portal vein

A

Glucokinase

4
Q

Can phosphorylate glucose and other hexoses

A

Both Hexokinase and Glucokinase

5
Q

It acts to ensure an adequate rate of glycolysis to meet the liver’s needs

A

Hexokinase

6
Q

Present only in liver parenchymal cells and Islet cells of the pancreas

A

Glucokinase

7
Q

Has a low Km for glucose

A

Hexokinase

8
Q

High Vmax (Many enzymes) and Km (low affinity)

A

Glucokinase

9
Q

In the liver it is saturated and acting at a constant rate under all normal conditions

A

Hexokinase

10
Q

Liver activity induced by insulin

A

Glucokinase