Hi-Yield

Question 0

Suppresses the appetite center

Decrease beta-oxidation of fatty acids for fuel

Answer 0

TNF-alpha

Question 1

Irreversible catabolic reaction (wasting syndrome)

Increased in TNF-alpha

Answer 1

Cachexia

Question 2

Distant effects of a tumor unrelated to metastasis

May involve ectopic secretion of hormone

Answer 2

Paraneoplastic Syndrome

Question 3

State the underlying cancer for each syndrome:

1. Lambert-Eaton Myasthenia
2. Acanthosis nigricans
3. Hypertrophic osteoarthropathy (clubbing)
4. Trousseau Syndrome
5. Non-bacterial thrombotic endocarditis
6. Red Cell Aplasia
7. Nephrotic Syndrome

Answer 3

1. Lung carcinoma
2. Visceral Malignancies
3. Lung Ca
4. Pancreatic Ca
5. Colon Ca
6. Thymoma
7. Hodgkin’s Lymphoma / Lung Ca

Question 4

Tumor marker for:

Prostate Cancer

Answer 4

PSA, Prostate Acid Phosphatase

Question 5

Tumor marker for:
Colorectal and Pancreatic Cancer
Gastric Ca and Breast CA

Answer 5

CEA

Question 6

Tumor marker for:
Hepatocellular CA
Non-seminomatous GCT (yolk sac)

Answer 6

AFP

Question 7

Tumor marker for:
Hydatidiform mole
Choriocarcinoma
Gestational Trophoblastic Tumor

Answer 7

beta-HCG

Question 8

Ovarian, Malignant Epithelial Tumors

Answer 8

CA-125

Question 9

Tumor marker for:

Melanoma, Neural Tumors, Astrocytoma

Answer 9

S-100

Question 10

Metastases to bone, Obstructive biliary disease, Paget Disease of the bone

Answer 10

Alkaline Phosphatase

Question 11

Tumor marker for:

Neuroblastoma, Lung and Gastric CA

Answer 11

Bombesin

Question 12

Tumor marker for:

Hairy Cell Leukemia (B-Cell Neoplasm)

Answer 12

TRAP

Question 13

Pancreatic Adenocarcinoma

Answer 13

CA-19-9

Question 14

Chemotherapy causes release of break-down products of dying cancer cells

Multiple electrolyte abnormalities:
Hyperkalemia
Hyperphosphatemia
Hyperuricemia
HYPOcalcemia

Answer 14

Tumor Lysis Syndrome

Question 15

List the order of origin that metastasize to the brain

Answer 15

Lung
Breast
Skin (melanoma)
Kidney
Gastrointestinal

Question 16

List in order of origin cancer that metastasizes to the liver

Answer 16

Colon
Stomach
Pancreas
Breast
Lung

Question 17

List in order of origin cancer that metastasizes to the bone

Answer 17

Prostate (Osteoblastic)
Thyroid (follicular)
Testes
Breast (lytic and blastic)
Lung (lytic)
Kidney

Question 18

Where is ADH and Oxytocin produced?

Answer 18

(SAPOx)
Supraoptic Nucleus
ADH
Paraventricular Nucleus
Oxytocin

Question 19

MEN-I

Wermer Syndrome

Answer 19

Parathyroid Adenoma / Hyperplasia
Pancreatic tumor
Pitiutary Tumor

Question 20

MEN-2A (Sipple Syndrome)

Answer 20

Pheochromocytoma
Medullary Carcinoma
Parathyroid Hyperplasia

Question 21

MEN-2B

Answer 21

Pheochromocytoma
Medullary Carcinoma
Neuroma / Ganglioneuroma