High-Throughput Sequencing

Question 1

De novo sequencing

Answer 1

Determining the complete sequence of the first genome from a species with no point of reference

Question 2

Resequencing

Answer 2

Determining the sequence of an individual of a species for which a reference genome sequence is already known

Question 3

Exome sequencing

Answer 3

Resequencing project that sequences only exons/coding regions by identifying trait-linked mutations protein-coding region