HIGH YIELD

Question 1

ENHANCEMENT OF PHAGOCYTOSIS BY COATING OF FOREIGN PARTICLES WITH SERUM PROTEINS

Answer 1

OPSONIZATION

Question 2

Jenner’s work with cowpox which provided immunity against smallpox demonstrates

Answer 2

CROSS IMMUNITY

Question 3

The structure formed by the fusion of engulfed material and enzymatic granules within the phagocytic cell

Answer 3

phagolysosome

Question 4

Two primary lymphoid organs

Answer 4

Bone marrow and thymus

Question 5

Receptor on T cells responsible for rosetting with sheep RBC

Answer 5

CO2

Question 6

Antigen binding sites in typical IGM

Answer 6

10

Question 7

Antibody best at agglutination and complement fixation

Answer 7

IgM

Question 8

Also known as T cell growth factor

Answer 8

IL-2

Question 9

The classical complement pathway is activated by

Answer 9

Ag-Ab complexes

Question 10

Role of properdin in the alternative pathway

Answer 10

Stabilization of C3/C5 convertase

Question 11

Factor H acts by competing with __ for the same binding site

Answer 11

Factor B

Question 12

A technologist who observes a red rash on her hands after removing her gloves

Answer 12

LAtex allergy

Question 13

In the chain of infection, a contaminated work area would serve as

Answer 13

Source

Question 14

The only biological waste that does not have to be discarded in a container with a biohazard symbol

Answer 14

urine

Question 15

AN employee who receives an accidental needle stick should immediately

Answer 15

notify a supervisor

Question 16

The first thing to do when acid is spilled on the skin is to

Answer 16

flush area with water

Question 17

When. combining acid and water

Answer 17

Acid is added to water

Question 18

To determine the chemical characteristics of sodium azide an employee would consult the

Answer 18

MSDS

Question 19

Normal ratio of CD4 and CD8

Answer 19

2:1

Question 20

Orchestrator or master regulator of the immune system

Answer 20

Helper T cell

Question 21

Refer to as the leukocyte common antigen (LCA)

Answer 21

CD45

Question 22

Referred to as the common acute lymphoblastic leukemia antigen (CALLA)

Answer 22

CD10

Question 23

Immature dendritic cells within the epidermidis

Answer 23

Langerhans cells

Question 24

MHC-1 restricted T cell that recognizes endogenous peptides

Answer 24

Cytotoxic T cell (CD8)

Question 25

MHC-II restricted T cell that recognizes exogenous peptides

Answer 25

Helper T cell (CD4)

Question 26

Change in the class of antibody being produced by the plasma cell

Answer 26

Isotype switching

Question 27

Change in the class of antibody being produced by the plasma cell

Answer 27

Isotype switching

Question 28

Efficiency of immunoglobulin G transfer across placenta

Answer 28

IgG1>IgG3>IgG4>IgG2

Question 29

Immunoglobulin that can activate the Alternative pathway

Answer 29

IgA

Question 30

Also know as millionaire antibody

Answer 30

IgG

Question 31

Immature lymphocytes that recognize self-antigens in the central (generative) lymphoid organs are killed by apoptosis

Answer 31

Central tolerance/ Clonal deletion

Question 32

Mature lymphocytes that recognize self-antigens in peripheral tissues become functionally inactive

Answer 32

Peripheral tolerance/ Clonal anergy

Question 33

CREST syndrome

Answer 33

anti-centromere

Question 34

X-linked immunodeficiency disorder characterized by the failure of B-cell precursors (pro-B cells and pre-B cells) to mature into B cells

Answer 34

Bruton’s Agammaglobulinemia

Question 35

Risk of transmission of HIV is ___ with needle stick injury whereas the risk of hepatitis B is 30%

Answer 35

0.03%

Question 36

Potential reservoir of HIV

Answer 36

Follicular dendritic cell

Question 37

Most common cancer seen in px with AIDS

Answer 37

Kaposi’s sarcoma

Question 38

Most sensitive SCREENING test for HIV

Answer 38

ELISA

Question 39

Most specific CONFIRMATORY test for HIV

Answer 39

Western Blot

Question 40

Most important initial test before considering a kidney transplant donor

Answer 40

Test for ABO

Question 41

The only blood group system that affects clinical transplantation

Answer 41

ABO

Question 42

HSV generally found in and around the ORAL cavity and in skin lesions that occur above the waist

Answer 42

HSV-1

Question 43

Cross-reacting herpes

Answer 43

HSV-1 and HSV-2

Question 44

HSV isolated primarily from the genital tract and skin lesions below the waist

Answer 44

HSV-2

Question 45

Potential marker for stone disease Cytokine that induces secretion of Ig and is a major factor in induction of the acute phase rnx; originally called interferon-B2 or B cell-stimulating factor-2

Answer 45

IL-6

Question 46

Information about the patient such as name, gender, age, or birth date, referring or attending physician

Answer 46

Patient demographics

Question 47

Anticoagulant for microlymphocytotoxicity testing

Answer 47

Acid citrated dextrose (ACD)

Question 48

Lymphocyte population

Answer 48

TBNK T-cells (60%-80%) B-cells (10%-20%) NK cells (<10%)

Question 49

Complement-dependent cytotoxicity uses this type of microscope

Answer 49

Inverted phase contrast microscope

Question 50

IN fluorescence polarization immunoassay (FPIA) the degree of fluorescence polarization is ____ proportional to concentration of analyte

Answer 50

INVERSELY

Question 51

Hallmark rash of measles infection; bluish white spots with a red halo located on the buccal or labial mucosa

Answer 51

Koplik’s spot

Question 52

Antigenic determinant

Answer 52

EPITOPE

Question 53

Part of the antibody that binds to the antigen

Answer 53

PARATOPE

Question 54

Immortal cell that produces antibodies Plasma cell fused with myeloma cells

Answer 54

HYbridoma cells

Question 55

Classic procedure for determining the HLA phenotype

Answer 55

Complement-Dependent Cytotoxicity test

Question 56

Acute phase reactant that is useful as a marker of sepsis and is utilized for differentiating bacterial and non-bacterial meningitis

Answer 56

PROCALCITONIN

Question 57

Gold standard in testing for contact dermatitis

Answer 57

PATCH TEST

Question 58

Gold standards of EBV serology methods

Answer 58

IFA (Indirect Immunofluorescence Assay)

Question 59

Gold standard for enumerating CD4 T cells

Answer 59

Immunophenotyping with flow cytometry

Question 60

Gold standard for detecting hepatitis C virus and monitoring therapy

Answer 60

RT-PCR