High Yield

Question 1

Anemia caused by trimethoprim

Answer 1

Megaloblastic anemia

Question 2

Anti-bacterials that cause hemolysis in G6PD-deficient patients

Answer 2

Sulfonamides

Question 3

Anti-emetics used in association with anti-cancer drugs that are 5-HT3 (serotonin receptor subtype ) antagonist

Answer 3

Odansetron, granisetron, dolasetron, palonosetron

Question 4

Blows DNA (breaks DNA strands), limiting SE in pulmonary fibrosis

Answer 4

Bleomycin

Question 5

Common side effect of Rifampin

Answer 5

Orange urine discoloration

Question 6

DOC for bipolar affective disorder

Answer 6

Lithium

Question 7

DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas

Answer 7

Metronidazole

Question 8

DOC for herpes and its MOA

Answer 8

Acyclovir; activated by viral thymidine kinase, results in inhibition of viral DNA replication

Question 9

DOC for influenza A and B

Answer 9

Oseltamivir or Zanamivir

Question 10

DOC for N. gonorrhea

Answer 10

Ceftriaxone

Question 11

DOC for RSV

Answer 11

Ribavirin

Question 12

Drug used for MRSA

Answer 12

Vancomycin

Question 13

HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism

Answer 13

Protease inhibitors

Question 14

May protect against doxorubicin cardio-toxicity by chelating iron

Answer 14

Dexrazoxane

Question 15

Meningitis prophylaxis in exposed patients

Answer 15

Rifampin

Question 16

MOA of sulfonamides

Answer 16

Inhibit dihydropteroate synthase

Question 17

Patients being treated with lithium, who are dehydrated, or taking diuretics concurrently, could develop

Answer 17

Lithium toxicity, lithium-induced nephrogenic diabetes insipidus

Question 18

SE of lithium

Answer 18

Tremor, sedation, ataxia, aphasia, thyroid enlargement, and reversible diabetes insipidus

Question 19

TCA used in chronic pain, enuresis, and OCD

Answer 19

Imipramine

Question 20

Technique used to diagnose perianal itching, and the drug used to treat it

Answer 20

Scotch tape technique
and mebendazole

Question 21

Treatment for TB patients (think RIPE)

Answer 21

Rifampin, Isoniazid, Pyrazinamide, and Ethambutol

Question 22

Unicyclic antidepressant least likely to affect sexual performance, used for management of nicotine withdrawal, SE’s include dizziness, dry mouth, aggravation of psychosis, and seizures

Answer 22

Bupropion

Question 23

Anti-estrogen used for estrogen receptor + breast cancer

Answer 23

Tamoxifen

Question 24

Binds tubulin and prevents the disassembly of microtubules during the M phase of the cell cycle inducing mitotic arrest

Answer 24

Paclitaxel (taxol)

Question 25

Cheap wide spectrum antibiotic DOC of otitis media

Answer 25

Amoxicillin

Question 26

Drug of choice for tx of pseudomembranous colitis

Answer 26

Metronidazole

Question 27

Interaction with this drug requires dose reduction of 6-MP

Answer 27

Allopurinol

Question 28

MOA of fluoroquinolones

Answer 28

Inhibit DNA gyrase (topoisomerase II) and topoisomerase IV

Question 29

Vancomycin MOA

Answer 29

Binds D-Ala-D-Ala on murein monomers and prevent polymerization of the murein monomers