high yield

Question 1

coagulase on ?

Answer 1

S. aureus

Question 2

TSST uses ___?

Answer 2

super antigens

Question 3

Glycocalyx on?

Answer 3

Staph epidermis

Question 4

Strep pyogen has _ protein

Answer 4

M

Question 5

M protein on ?

Answer 5

Strep - pryogenes

Question 6

Who has antiphagocytic polysaccarhides capsule

Answer 6

strep pneumoniae

Question 7

3 main causes of endocaridits bugs

Answer 7

S. aureus, Coagulase negative staph (so basically all staph)

Strep viridan

Question 8

Rheumatic heart disease from which bug?

Answer 8

Strep pygoens (strep)

Question 9

Dextran made by ?

Answer 9

viridans streptococci

Question 10

Classify N. gonorrhoeae

Answer 10

Gram neg, diplo-cocci

Question 11

Drug enter CSF

Answer 11

cephalosporin 3/4
Metronidzaole
Chloroamphenicol
Sulfoamides/trimethoprim
Rifampin

Question 12

Drug enter CSF with inflammation

Answer 12

vanco
penicillin
ciprofloxacin
Tetracycline

Question 13

Drug enter CSF Poor

Answer 13

Aminoglycosides
Cephalosporin 1/2
erythromycin
clindamycin

Question 14

Drugs fetus/pregnancy

Answer 14

aminoglycosides, variconazole, metronidazole, chloroamphenicol, tetracycline, fluoroquinolone

Question 15

Bone accumulation

Answer 15

Clindamycin

Question 16

accumulation lungs

Answer 16

macrolides

Question 17

accumulation peridonitis/acne

Answer 17

tetracyclines

Question 18

UTI accumulation

Answer 18

Nitrofurantonin

Question 19

accumulation 8th nerve/renal

Answer 19

aminoglycosides

Question 20

accumulation in bone/teeth bad

Answer 20

tetracycline in kids

Question 21

B-ALL markers

Answer 21

CD19, CD22, CD79a

NO CD20/surface IgX (not mature)

Question 22

T-ALL markers

Answer 22

CD2, 3, 7
CD4/8
CD99, CD1a

Question 23

ALL general markers

Answer 23

CD34, TdT

HLA-DR

Question 24

B-all diseases genes/prognosis/age

Answer 24

BCR-ABL(9:22) worst - adults
MLL t11q23 poor - baby
ETV6-RUNX1 (t12;21) - good - children

Question 25

T-ALL prognosis, patient profile

Answer 25

Good (better young) Males Mediastinal mass

Question 26

AML markers

Answer 26

CD34, HLADR, CD38 (immature) | CD117 (Ckit), MPO - myeloid markers

Question 27

CD 34 =?

Answer 27

immature

Question 28

CD117

Answer 28

myeloid

Question 29

MPO

Answer 29

myeloid

Question 30

TdT

Answer 30

lymphoid

Question 31

Name AML disesases (6)

Answer 31

``` MLL 11q23 - poor RUNX1-RUNX1T1 (t8:21) good - young RBM15-MKL1 t(1:22) infant good PML-RARA t(15;17( APL) - good 2 t-aml - therapy ```

Question 32

APL 2 things to know

Answer 32

treat with ATRA and risk for DIC

Question 33

Aklyating agent --> MDS time

Answer 33

2-8 years; MDS --> AML | chr 5/7

Question 34

Topo agent --> effect

Answer 34

1-2 yr; MLL 11q23

Question 35

Three indicators of AML

Answer 35

FLT3-ITD NPM1 CEBPA

Question 36

MDS types

Answer 36

RCUD RCMD RAEB1 RAEB2

Question 37

SLL/CLL markers

Answer 37

CD23 | SMudge cell

Question 38

Follicular lymphoma markers

Answer 38

BCL2 - prevents apoptosis (CD19, 20, 10, BCL6) t(14:18)

Question 39

Mantle Cell lymphoma

Answer 39

t(11:14) BCL1 - G1->S cell cycle (CD5, 10, 20)

Question 40

Burkitt's lymphoma describe

Answer 40

t(8:14) Starry sky appearence MYC

Question 41

Plasma cell - multiple myeloma signs

Answer 41

CRAB: high ca, renal insuff, anemia, bone lesion | M protein spike

Question 42

CHL

Answer 42

RS cells CD30 CD 15 Nodular sclerosis - broad collagen bands

Question 43

Immunopathology types 1-4 basics

Answer 43

1 - allergies - IgE 2 - B cell - anitbody to self 3 - C complement 4 - Delayed/Tcell

Question 44

SCID affects

Answer 44

T and B

Question 45

Bruton's X linked affects

Answer 45

B

Question 46

affects X linked hyperIGM

Answer 46

class switch

Question 47

CVID affects

Answer 47

no Ab

Question 48

affects Digeorge

Answer 48

``` absent T (stroma cells) CATCH22- cardiac, ab face, thymic aplasia, celft palate, hypocal, chr 22 ```

Question 49

lacunar cells in

Answer 49

nodular sclerosis - CHL

Question 50

CHL symptoms

Answer 50

fever, night sweats, painless lymphadenopathy, nephrotic syndrom/hypercalcemia