histology Flashcards

(28 cards)

1
Q

what are the bundles called that muscle fibres are grouped into

A

fascicles

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2
Q

what is epimysium

A

the connective tissue that surrounds the muscle as a whole

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3
Q

what is perimysium

A

the connective tissue around a single fascicle

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4
Q

what is endomysium

A

the connective tissue around a single muscle fibre

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5
Q

what are sarcomeres

A

the unit f contraction of the muscle cell, smallest contractile elements in the striated muscle cell

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6
Q

how long does a sarcomere extend

A

from one Z line to the next

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7
Q

what does a motor unit consist of

A

one motor neurone and all of the muscle fibres that innervates it

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8
Q

what is type 1 muscle fibre

A
  • slow contracting that depend on oxidative metabolism
  • mitochondria and myoglobin
  • resistant to fatigue
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9
Q

what is type 2A fibres

A
  • intermediate
  • relatively fast
  • reasonably resistant to fatigue
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10
Q

what is type 2B fibres

A
  • fast contracting
  • depend on anaerobic metabolism
  • few mitochondria and less myoglobin
  • fatigue easily
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11
Q

where are chondrocytes found

A

a space in the extracellular matrix called a lacuna

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12
Q

how is type II collagen different from type I

A

its finer and forms 3D meshwork

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13
Q

what are proteoglycan aggregates made up of

A

GAGs bound to a core protein and often linked to hyaluronan

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14
Q

colour of hyaline cartilage

A

blue-white and translucent

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15
Q

colour of elastic cartilage

A

light yellow

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16
Q

colour of fibrocartilage

17
Q

examples of where hyaline cartilage is found

A

articular surfaces
tracheal rings
costal cartilage
epiphyseal growth plates

18
Q

functions of bone

A
support
levers
protection
calcium store
haemopoiesis
19
Q

what are the two types of bone

A

cancellous and cortical

20
Q

what are cement lines

A

the lines that are often visible surrounding the osteon

21
Q

does trabecular bone have haversian canals

22
Q

what are osteoprogenitor cells

A

located on bone surfaces, for example under the periosteum, these cells serve as a pool of reserve osteoblasts

23
Q

what are osteoblasts

A

bone forming cells found on the surface of developing bone.

24
Q

what are osteocytes

A

a bone cell trapped within the bone matrix.

25
what are osteoclasts
large (up to 40µm or more) multinucleated cells. They are found on the surface of bone and are responsible for bone resorption.
26
what is the basic multicellular unit
the collection of osteoclasts and osteoblasts that participate in bone remodelling
27
how does bone remodelling work
In this process, a number of osteoclasts will congregate and begin to ‘drill’ into the bone, forming a tunnel. A blood vessel will grow into the tunnel bringing with it osteoblasts which line the tunnel and begin laying down new lamellar bone. This process continues until only the space of a Haversian canal remains.
28
what is osteoid
when the osteoblasts secrete collagen, glycosaminoglycans, proteoglycans and other organic components this matrix is called osteoid