Histology Of Stomach

Question 1

3 regions of stomach

Answer 1

Cardiac
Pyloric
Fundus

Question 2

Mucosa of stomach

Answer 2

Simple columnar epithelium
Folds or rugae
Gastric pits

Question 3

Submucosa of stomach

Answer 3

Loose and distensible
Contains blood vessels

Question 4

Muscularis of stomach

Answer 4

Inner circular layer reinforced by a inner oblique layer, outer longitudinal layer

Question 5

Serosa of stomach

Answer 5

Covered by mesothelial layer

Question 6

Fundic/gastric glands

Answer 6

Simple, branched, tubular glands, tightly packed and extend from the bottom of the gastric pits to the
muscularis mucosae

Question 7

Isthmus of the fundic
gland is a

Answer 7

site of the stem cell’s location

Question 8

Glands extend from the bottom of the ___ to the ___

Answer 8

gastric pits to the muscularis mucosae

Question 9

Five major cell types

Answer 9

Mucous cells
Chief cells
Parietal cells
Gastroenteroendocrine cells
Stem cells

Question 10

Surface mucous cells lines the

Answer 10

surface and the gastric pits

Question 11

Shape and function of gastric mucous cells

Answer 11

Simple columnar
Secrete mucus to protect from acid

Question 12

Mucus neck cells shape and function

Answer 12

Less columnar than the surface mucous cells lining
the gastric pits
• Their mucus secretion is less
alkaline than that of the surface epithelial mucous cells and is more soluble

Question 13

Why do parietal cells have abundant mitochondria

Answer 13

provide the (ATP) to pump H+ ions into the lumen of the secretory canaliculus

Question 14

Function of parietal cell

Answer 14

Secrete HCl (digestion) and intrinsic factor(absorb B12)

Question 15

Chief cells secrete ___

Answer 15

Pepsinogen

Question 16

Enteroendocrine cells secrete ___

Answer 16

Peptide hormones

Question 17

Function of Peptide hormones

Answer 17

1. Regulation of water, electrolyte metabolism and enzyme secretion
2. Regulation of gastrointestinal motility and mucosal growth
3. Stimulation of the release of other peptide hormones

Question 18

Closed Enteroendocrine cells

Answer 18

rest on the basal lamina and do not always reach the lumen

Question 19

Open Enteroendocrine cells

Answer 19

have a thin cytoplasmic extension bearing microvilli that are exposed to the gland lumen.
• Serve as chemoreceptors

Question 20

Predominant cell in pyloric glands

Answer 20

Mucus-secreting cell

Question 21

What cells are in the lamina propria

Answer 21

fibroblasts and cells of the immune system, namely, lymphocytes, plasma cells, macrophages, and some eosinophil

Question 22

Which plexus is in the submucosa

Answer 22

Meissner’s plexus

Question 23

Which plexus is in the muscularis externa

Answer 23

Myenteric or Auerbach’s plexus

Question 24

Serosa is continuous with the 1 of the abdominal cavity via the greater omentum and with 2

Answer 24

1) parietal peritoneum
2) visceral peritoneum

Question 25

Enteric Nervous System is Primarily responsible for innervating the

Answer 25

smooth muscle layers of the alimentary canal

Question 26

Epithelial Transformation Zone At the gastro-esophageal junction

Answer 26

transition from the stratified squamous epithelial lining of the esophagus to a simple mucus-secreting columnar epithelium of the stomach