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Flashcards in Histology Of The Urinary Tract Deck (21):
0

What is found at the vascular and urinary poles of the renal corpuscle?

Vascular pole - afferent/efferent arterioles and glomerulus
Urinary pole - Bowman's capsule

1

How does the Bowman's capsule develop?

Renal tubule is derived from the ureteric bud. Envelopes the growing glomerulus, resulting in a double layers cover - the Bowman's capsule.

2

Function of the renal corpuscle?

Produce an ultrafiltrate of the plasma

3

Epithelium of the parietal layer of Bowman's capsule?

Simple squamous

4

What is the filtration barrier made up of?

Visceral layer of Bowman's capsule
Fenestrated capillary endothelium with podocytes invested in it

5

What role does the parietal layer of Bowman's capsule play in filtration?

Forms a funnel to collect the ultrafiltrate to drain into PCT

6

Epithelium of the proximal convoluted tubule?

Simple cuboidal with a brush border

7

What are the four parts of the loop of Henle?

Pars recta
Thin descending limb*
Thin ascending limb
Thick ascending limb*

*only parts you need to think about for function

8

What is the epithelium of the thin descending limb? Significance of this?

Simple squamous - means there is no active transport

9

How do you differentiate between the thin descending limb and a capillary on a sample?

Capillary will have red blood cells

10

Epithelium of the thick ascending limb? Significance of this?

Simple cuboidal
Can do active transport

11

How can you tell the difference between the thick ascending limb and PCT?

PCT has a brush border

12

Epithelium of the distal convoluted tubule?

Simple cuboidal

13

How can you tell the difference between PCT and DCT?

DCT has no brush border and a larger lumen

14

What is the juxtaglomerular apparatus?

The area where the DCT a makes contact with the parent glomerulus

15

What is the juxtaglomerular apparatus made up of?

Macula densa - dense staining region
Juxtaglomerular cells - cells of the afferent arteriole
Extraglomerular mesangial cells - occupy space between glomerulus and tubular system

16

Epithelium of collecting duct?

Simple cuboidal

17

How can you tell the difference between the CD and ascending limb?

CD has a larger lumen that is more irregular than circular

18

Describe the renal pyramid

Where progressively larger ducts merge and empty at the renal papilla to form a pyramid shape.

19

Describe the histology of the ureter

Two layers of smooth muscle - a third appears in the lower third of the ureter
Lined by transitionary epithelium/urothelium

20

Histology of the bladder?

Three layers of smooth muscle
Urothelium which is stratified
Adventitia