Histopathology Buzzwords Flashcards
(88 cards)
Malignancy
multiple emboli
no cardiac murmurs
echo shows vegetations
BCs neg
non-bacterial thrombotic endocarditis
Sterile fibrin and platelet vegetations are
present on cardiac valves
non-bacterial thrombotic endocarditis
tall, long limbs and long thin fingers
aortic regurg murmur
tearing chest pain radiating to back
marfan’s syndrome
Cystic medial necrosis = focal degeneration of elastic tissue and muscle fibres in the tunica media -> aneurysm
Marfan’s syndrome
How long after MI?
- extensive cell infiltration including polymorphs and macrophages
- extensive debris post necrosis and the cytoplasm is homogeneous
- no evidence of
collagenization or a scar
1-4 days
Arteries have onion skin appearance
Raynaud’s phenomenon
Swelling and stiffness of fingers
Diffuse Scleroderma
Anti-topoisomerase
Periorbital oedema
Purple Heliotrope rash on eyelids
Erythematous scaling rash on face
High SK-M enzymes
Dermatomyositis
MS patient has plaques, what is their classification (ICDNS):
presence of oedema and macrophages, and some myelin breakdown
Early chronic active plaque
Brain atrophy
loss of neurons
senile plaques
neurofibrillary tangles
Alzheimer’s disease
Phosphorylated tau protein
Aggregation of beta-amyloid
Alzheimer’s Disease
Cell change - Oesophageal biopsy shows columnar epithelium with goblet cells
Metaplasia
Barrett’s oesophagus is a change between what?
normal stratified squamous epithelium -> columnar epithelium
Histological examination of pancreas - parenchymal fibrosis and large
ducts containing insipissated secretions
chronic pancreatitis
Histology
shows chronic inflammation with parenchymal fibrosis, loss of pancreatic
parenchymal elements and duct strictures with formation of intrapancreatic calculi. Jaundice may occur; it is a presenting feature in
only a small proportion of patients and would be secondary to common
bile duct obstruction during its course through the fibrosed head of the
pancreas. Grossly, the pancreas is replaced by firm fibrous tissue within
which are dilated ducts and areas of calcification
Gutalim Acid Decarboxylase (GAD) antibody positive
Diabetes mellitus type 1
AMA antibody associated with which autoimmune conditions
Rheumatoid arthritis
Scleroderma
Primary biliary cirrhosis
Mutation of the copper transport ATPase gene on Ch13
Wilson’s disease
Arthritis
Myositis
Uveitis
Erythema nodosum
Pyoderma gangrenosum
Primary Sclerosing Cholangitis
Ulcerative Colitis
Chlamydia trachomatis infection
USS shows hydrosaplinx, which is a complication of?
Salpingitis
Hydrosalpinx,
a complication of salpingitis, is the dilation of the fallopian tube that is
thin-walled and contains clear fluid. This is believed to be a sequel to
previous inflammatory damage to the tube. The scarring sequelae are
believed to include plical fusion, adhesions to the ovary, tubo-ovarian
abscess, peritonitis, hydrosalpinx, infertility and ectopic pregnancy.
Dysmenorrhoea
Multiple large rounded nodules, well-circumscribed
With pseudocapsule
Fibroid, aka Leiomyoma
Acute onset severe abdo pain
USS shows mass in ovary with three embryonic germ cell layers
Cystic Teratoma of the ovary - torsion presentation
IDA blood film
Hypochromic and microcytic red blood cells with anisopoikilocytosis and
no evidence of basophilic stippling
Serological and histological findings of Coeliac Disease
Anti-endomysial antibodies and anti-tissue transglutaminase antibodies/
villous atrophy, crypt hyperplasia, increased intraepithelial lymphocytes
Shepherd’s crook deformity
polyostotic fibrous displasia - varus angulation of the proximal femur
Loose fibrous tissue with metaplastic immature or woven bone trabeculae arranged in Chinese letters formation
Fibrous dysplasia
