Histopathology Practical 5

Question 1

Question 2

Answer 2

cholangiohepatitis

inflammation effects bile ducts and liver itself

Question 3

Answer 3

portal triad
red: bileduct
blue : thick walled a. hepatica —> fresh blood from heart
green: portal vein

Question 4

Answer 4

cholangiohepatitis

portal triad
limiting plate

Question 5

Answer 5

cholangiohepatitis

Question 6

Answer 6

cholangiohepatitis

portal triad , you can see inflammatory area compared to normal tissue

inflammatory cells: mononuclear

Question 7

Answer 7

cholangiohepatitis

bile duucts

lymphocytes
mononuclear inflammatory cells

Question 8

Answer 8

cholangiohepatitis

bile duucts

lymphocytes
mononuclear inflammatory cells

Question 9

Answer 9

rubarths disease
caused by canine adenovirus 1 hepatis

enlarged and shiney liver

Question 10

Answer 10

rubarths disease
caused by canine adenovirus 1 hepatis

portal and sinusoidal inflammatory infiltration

green arrow: cowdry A- type intranuclear inclusion body

Question 11

Answer 11

rubarths disease
caused by canine adenovirus 1 hepatis

cowdry A- type intranuclear inclusion body

Question 12

Answer 12

rubarths disease
caused by canine adenovirus 1 hepatis

cowdry A- type intranuclear inclusion body

Question 13

Answer 13

rubarths disease
caused by canine adenovirus 1 hepatis

necrosis

Question 14

Answer 14

rubarths disease
caused by canine adenovirus 1 hepatis

green : necrosis
red: not healthy liver tissue, but functional

Question 15

Answer 15

rubarths disease
caused by canine adenovirus 1 hepatis

red area: necrosis
green : cowdry A- type intranucl. inclusion body
usually next to necrosis

Question 16

Answer 16

rubarths disease
caused by canine adenovirus 1 hepatis

blue: apoptosis
green: cowdry A- type intranucl. inclusion body

Question 17

Answer 17

rubarths disease
caused by canine adenovirus 1 hepatis

necrotic zone with hyperaemic rim around

you can also spot some inflamamtory cells arounds

Question 18

Answer 18

rubarths disease
caused by canine adenovirus 1 hepatis

upper part is normal liver parenchyma

lower part is necrotic, due to viral effect–> know it is viral if you see intranuclear inclusion bodies which is shown on the arrows

Question 19

Answer 19

Liver cirrhosis
chronic condition –> scar tissue

Question 20

Answer 20

Liver cirrhosis
regenerative nodules

Question 21

Answer 21

Liver cirrhosis

pseudolobulus–> smaller part of liver tissue without central vein in the middle

Question 22

Answer 22

liver cirrhosis

pseudolobulus with azan staining
stains collagen blue

Question 23

Answer 23

Liver cirrhosis

pseudolobule

Question 24

Answer 24

Liver cirrhosis

bile duct proliferation

Question 25

Answer 25

Liver cirrhosis ductal proliferation

Question 26

Answer 26

Liver cirrhosis silver staining

Question 27

Answer 27

Paratuberculosis enlargment in ln of mesenterica

Question 28

Answer 28

Paratuberculosis proliferative innflammation mucous membrane of ileum look like brain

Question 29

Answer 29

Paratuberculosis

Question 30

Answer 30

Paratuberculosis green: enteric mucosa with some inflammatory cells, can still se villi blue: proliferation of histocytes --> can find langhans gigant cells proliferation due to lack of TNf alpha producton

Question 31

Answer 31

Paratuberculosis ziehl nielsen staining to detect mycobacteria --> red

Question 32

Answer 32

Paratuberculosis epitheloid cells

Question 33

Answer 33

parvoviral necrotic- haemorrhagic enteritis necrotic of small intestine enlarged ln in mesenterica

Question 34

Answer 34

parvoviral necrotic- haemorrhagic enteritis necrotic mucosa ( payers patches ?!?!?!?!?!? says so in the video, mucosa above sunken in )

Question 35

Answer 35

parvoviral necrotic- haemorrhagic enteritis necrosis

Question 36

Answer 36

parvoviral necrotic- haemorrhagic enteritis looks like internuclear infusion bodies features, but he says in the video that you can not be sure that it is

Question 37

Answer 37

parvoviral necrotic- haemorrhagic enteritis proliferation

Question 38

Answer 38

parvoviral necrotic- haemorrhagic enteritis proliferation increased mitosis marked: myotic figures

Question 39

Answer 39

parvoviral necrotic- haemorrhagic enteritis payers patches

Question 40

Answer 40

parvoviral necrotic- haemorrhagic enteritis center of lymphoid follicle replicating lymphoid cells --> b-cells--> target for virus

Question 41

Answer 41

parvoviral necrotic- haemorrhagic enteritis blue : muscularis green : submucosa red: serous membrane above muscularis you can see that crypts and villi is missing --> necrosis

Question 42

Answer 42

parvoviral necrotic- haemorrhagic enteritis villi and crypts is missing --> necrosis

Question 43

Answer 43

parvoviral necrotic- haemorrhagic enteritis no recognizable epithelial tissue --> necrosis

Question 44

Answer 44

acute purulent leptomeningitis glaesserella parauis / streptococcus suis glasser disease pia mater is thickened brain tissue is intact

Question 45

Answer 45

acute purulent leptomeningitis glaesserella parauis / streptococcus suis glasser disease extremely dialated blood vesssel / microtrombus

Question 46

Answer 46

acute purulent leptomeningitis glaesserella parauis / streptococcus suis glasser disease extremely dialated blood vessel / microthrombus

Question 47

Answer 47

acute purulent leptomeningitis glaesserella parauis / streptococcus suis glasser disease inflammation purrulent : nutrophil granulocytes thrombosis: with eosinic cells inside asweell

Question 48

Answer 48

acute purulent leptomeningitis glaesserella parauis / streptococcus suis glasser disease inflammation purrulent : nutrophil granulocytes thrombosis: with eosinic cells inside asweell

Question 49

Answer 49

Encephalitis caused by listeria monocytogenes

Question 50

Answer 50

Encephalitis caused by listeria monocytogenes darker are is effected meningis or pia mater is not thickened/ affected -- key point to differentiate from glasser disease

Question 51

Answer 51

Encephalitis caused by listeria monocytogenes lesion in brain = encephalitis pia mater is not thickened

Question 52

Answer 52

Encephalitis caused by listeria monocytogenes red: perivascular cuffing blue: mononuclear

Question 53

Answer 53

Encephalitis caused by listeria monocytogenes micro abcesses nutrophils

Question 54

Answer 54

West Nile viral encephalitis normal thick pia mater/meningis

Question 55

Answer 55

West Nile viral encephalitis two types of lesion one is connected to blood vessels and some is not

Question 56

Answer 56

West Nile viral encephalitis extreme perivascular cuffing with mononuclear cells in multiple layers

Question 57

Answer 57

West Nile viral encephalitis infects neurons -->. phagocytosis --> glial scarring

Question 58

Answer 58

West Nile viral encephalitis infects neurons -->. phagocytosis --> glial scarring glial scarring

Question 59

Answer 59

West Nile viral encephalitis extreme perivascular cuffing with mononuclear cells in multiple layers