History Flashcards
(20 cards)
When was nitrous oxide first prepared? By whom?
1773 by Joseph Priestly
When was the first time NO was used for dental extraction? By whom?
1844 by Horace Wells
When was cocaine first used as a local anesthetic? By whom?
1884 by Carl Koller
Who performed the first inferior alveolar nerve block? When?
William Halstead in 1884
What makes cocaine an unique anesthetic?
It is the only one that causes vasoconstriction
When was cocaine first extracted from coca leaves?
1856
Which drug was approved in the US in 1905?
Procaine
When was procaine approved in the US?
1905
What drug was approved in the US in 1948?
Lidocaine
When was lidocaine approved in the US?
1948
What drug was approved in the US in 1960?
Mepivacaine
When was mepivacaine approved in the US?
1960
What drug was approved in the US in 1965?
Prilocaine
When was prilocaine approved in the US?
1965
What drug was approved in the US in 1972?
Bupivacaine
When was bupivacaine approved in the US?
1972
What drug was approved in the US in 2000?
Articaine
When was articaine approved in the US?
2000
What is a chemical tourniquet? What is its purpose?
It is a combination of epinephrine and levonordefrin. Epinephrine reduces the uptake of local anesthetic, resulting in increased duration of action. Allows for: Prolonged effect of LA Increased depth of anesthesia Reduces plasma concentration of LA Reduces incidence of systemic toxicity Reduces bleeding at surgical site
When was ether first used? By whom?
1846 by William Morton
