History of psychiatric drugs and other interventions Flashcards
(22 cards)
Who introduced insulin shock therapy and when?
Sakel in 1933
Who introduced frontal leucotomy for psychosis and when?
Moniz
1935
Who introduced metrazol therapy and when?
Meduna
1935
Who introduced ECT and when?
Cerletti and Bini
1938
Who discovered lithiums beneficial effect in mania and when?
Cade
1949
Who synthesised chlorpromazine and when?
Charpentier
1950
Who discovered use of iproniazid (MAOI) and when?
Kline in 1951
WHo introduced chlorpromazine as a treatment for schizophrenia and coined the term neuroleptic and when?
Delay and Deniker
1952
Who discovered the antidepressant effects of imipramine and when?
Kuhn
1957
Who described the cheese effect in MAOI use and when?
Blackwell
1960s
Who coined the term antidepressant and when?
Lurie
1960s
who developed the first SSRI, which one and when?
Carlsson
Zimelidine
1972
Who reintroduced clozapine into clinical practice and when?
Kane
1988
What was clozapine synthesised from and when?
Imipramine in 1958
What year was fluoxetine first launched in the US?
1988
What was chlorpromazine initially used for, by who and when?
Anaesthetic in 1951 by Laborit and Huguenard
What was the first antidepressant initially used for?
TB
What was imipramine developed from ?
promethazine
When was imipramine approved for treatment of depression?
1959
Why was zimeldine removed from the market?
Severe side effects e.g. hypersensitivity reactions, GBS.W
When was the first report on fluoxetine published?
1974
