HLA Subtype Diseases

Question 1

A3

Answer 1

Hemochromatosis (too much iron in the body) Iron: Fe, A3

Question 2

HLA-B8

Answer 2

Addisons Disease, Myasthenia Gravis (the antibody ATE (8) the ACh receptors and the adrenal gland)

Question 3

HLA-B27

Answer 3

Psoriatic arthritis, Ankylosing spondylitis (inflammatory arthritis affecting spine and large joints), IBD-associated arthritis, Reactive arthritis

PAIR (seronegative arthopathies)

Question 4

HLA-DQ2/DQ8

Answer 4

Celiac Disease

I ate (8) too (2) much gluten at Dairy Queen

Question 5

HLA-DR2

Answer 5

Multiple sclerosis, Hay Fever, Lupus, Goodpasture Syndrome

“HEY this doctor is going TO be a GOOD MS”

Question 6

HLA-DR3

Answer 6

Diabetes mellitus type 1, SLE, Graves disease, Hashimoto thyroiditis, Addison’s Disease

Two, three SL-E-E (lupus)
Three four, not so sour (diabetes)

Question 7

HLA-DR4

Answer 7

Rheumatoid arthritis, diabetes mellitus type 1, addison disease

There are 4 walls in a “RHEUM” (room)

Question 8

HLA-DR5

Answer 8

Pernicious anemia (B12 def), Hashimoto thyroiditis