HMP shunt

Question 1

G6PD deficiency theres is absence of required NADPH, the consequence is…

Answer 1

Hemolysis

Question 2

Classic findingas in G6pd erithrocities:

Answer 2

Heinz bodies and bite cells

Question 3

Triggers of G6PD deficiency:

Answer 3

Infection;
Fava beans;
Drugs:
Antibiotics, Anti malarials, AAS Paracetamol;

Question 4

Treatment of G6pd:

Answer 4

Avoid of triggers;

Question 5

The HMP shunt serves two major purposes in cellular metabolism. It generates ribose 5-phosphate used in the synthesis of nucleic acids. It also produces NADPH, a substance used in a number of synthetic pathways. NADPH protects red cells against oxidative damage. It is also used as part of the respiratory burst in phagocytes. In addition, the enzyme fatty acid synthase requires NADPH. Fatty acid synthesis will be impaired in the absence of normal NADPH production by the HMP shunt.

Answer 5

True