HOCM

Question 1

Takotsubo cardiomyopathy

Answer 1

= broken heart syndrome

Stress induced cardiomyopathy, looks like Octopus on CMR

Question 2

Pathophys HOCM

Answer 2

predominantly diastolic dysfunction

LV hypertrophy -> decreased compliance - decreased output

“myofibrillar hypertrophy with chaotic + disorganized fashion myocytes (“disarray”) + fibrosis on biopsy”

Question 3

HOCM presentation

Answer 3

jerky pulse, large A waves, double apex beat

systolic murmurs
- ejection systolic - LV outflow obstruction
- pansystolic - due to systolic anterior motion of mitral valve !!

Question 4

What can increase \ decrease the ejection systolic murmur heard in HOCM

Answer 4

increases - valsava manoevre

Decreases - on squatting

Question 5

other conditions assoc with HOCM

Answer 5

Friedreichs ataxia

Wolff Parkinson white

Question 6

HOCM echo findings

Answer 6

MR SAM ASH

mitral regurg (MR)
Systolic anterior motion (SAM) of anterior mitral valve leaflet

Asymmetric hypertrophy (ASH)