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RT4110 > Hodgkin Lymphoma > Flashcards

Hodgkin Lymphoma Flashcards

1
Q

What is the staging system used to describe the features of Hodgkin lymphoma

A

The Ann Arbor Staging System

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2
Q

What letters can be included with the four stages of Hodgkin lymphoma?

A

A- The patient does not have B symptoms

B- The patient has B symptoms

E- Extranodal disease is present

S- Disease is found in the spleen

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3
Q

In advanced stages, what is the pattern of spread for Hodgkin lymphoma?

A

To the viscera, spleen, liver, bone marrow or other organs

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4
Q

What is the primary treatment modality for early stage Hodgkin Lymphoma?

A

Chemotherapy

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5
Q

For stage 1 & 2 Hodgkin lymphoma, what is the standard treatment regimen?

A

ABVD (Adriamycin, Bleomycin, Vincristine, Dacarbazine) chemotherapy

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6
Q

What is salvage therapy?

A

When chemotherapy is used after the disease has reoccurred in an area already treated with radiation therapy

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7
Q

True/false The progression of Hodgkin’s lymphoma is typically less predictable than that of non-Hodgkin’s lymphoma

A

false

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8
Q

Which Hodgkin’s lymphoma symptoms are under B category (multiple answers)
a) Fever
b) Coughing
c) Dysphagia
d) Frequent night sweats
e) Weight gain
f) Unexplained weight loss

A

a, d, f

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9
Q

What is the combined field name for the following fields

  1. Neck
  2. Chest
  3. Axilla
A

Mantle field

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10
Q

What is the combined field name for the following fields

  1. Pelvis
  2. Para-aortic fields
A

Inverted Y

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11
Q

What is the combined field name for:

mantle field
spleen
LNs in the upper abdomen and pelvic area

A

Total Nodal Radiation

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12
Q

What is the combined field name for:

mantle field
spleen
LNs in the upper abdomen

A

Subtotal Nodal Radiation

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13
Q

What is the combined field name for a treatment area that only encompass the areas of known disease?

A

Involved Field Radiation

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14
Q

What is the combined field name for a treatment area that includes areas of known disease and contiguous uninvolved LNs?

A

Extended Field Radiation

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15
Q

Why is treatment to pelvic region avoided?

A

To preserve fertility for patients with a favorable prognosis.

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16
Q

What should be done if there is a treatment failure for a Hodgkin lymphoma patient?

A
  1. Autologous bone marrow transplant
  2. Peripheral blood stem cell transplant.
17
Q

Before conducting a autologous bone marrow transplant or peripheral blood stem cell transplant, what must be done?

A

High doses of radiation/chemo to the whole body to destroy cancer cells & bone marrow tissue to suppress the immune system.

Immune system suppression helps prevent the body from rejecting the new stem cells.

18
Q

An individual requires a pelvic radiation treatment plan being built. What combined field is typically utilized with this type of case & what comprises the field?

A

Inverted Y ~ abdominal (para-aortic LNs) & Pelvic field

19
Q

(T or F) Radiation is more effective alone than utilized in conjunction with chemotherapy.

A

False; Radiation is more effective in conjunction with chemotherapy.

20
Q

For an individual that is receiving pelvic irradiation for HL (Hodgkin lymphoma), what is the dose range if radiation is given in conjunction with chemotherapy?

A

Up to 20 Gy

21
Q

For an individual that is receiving pelvic irradiation to an area free of disease, what is the dose range?

A

35 to 44 Gy

22
Q

For an individual that is receiving pelvic irradiation to an area of initial nodal involvement, what is the dose range?

A

25 to 30 Gy

23
Q

(T or F) When treating a large field size, it is crucial to spare as much healthy tissue

A

TRUE

24
Q

What are the two kinds of NHL?

A

Indolent and aggressive

25
Q

What kind of NHL has a better life expectancy?

A

Indolent

26
Q

(TRUE OR FALSE) The stomach is the most common place NHL will spread to.

A

TRUE

27
Q

What are the symptoms of NHL? (5)

A

Large lymph nodes
Night sweats
Weight loss
Fever
Itching

28
Q

What is needed in aiding a NHL diagnosis for a physician?

A

A complete history
Physical exam

29
Q

Imaging used to help stage and find the extent of the disease includes:

A

Chest x-rays
CT
PET
MRI
Ultrasound

30
Q

Which is the rarest form of classic Hodgkin lymphoma?

A

Lymphocyte Depleted Hodgkin Lymphoma

31
Q

What is the most common sign of Hodgkin lymphoma?

A

A painless mass found by patient above the diaphragm

32
Q

Hodgkin’s lymphoma accounts for this percentage of childhood cancers

A

6%

33
Q

What percentage of childhood Hodgkin’s lymphoma are cured?

A

95%

34
Q

What practices may reduce side effects in Hodgkin’s patients?

A

Adequate rest
Sun protection
Diet alterations

35
Q

HL is more common in males or females?

A

Males

36
Q

The presence of what cells have a correlation to HL?

A

Reed sternberg cells

RT4110 (9 decks)

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