Homeostasis Flashcards
(42 cards)
What is homeostasis?
The maintenance of a constant environment
-Involves constant changes around an optimum point
What is the importance of homeostasis?
-Changes in pH and temperature affect proteins e.g. enzymes
-Changes can cause a reduction in the rate of reaction
-Changes in water potential can change volumes in cells e.g expand or shrink
-Glucose concentration affects the glucose supply for respiration
How are the changes of homeostasis controlled?
-Optimum = point where reaction works best
-Receptor = detects change from optimum
-Coordinator = links the receptor and the effector
-Effector = muscle or gland which brings changes to return system to optimum
What is negative feedback?
-System deviates from optimum
-Change is detected by the receptor
-A change is then produced which returns the system back closer to the optimum
What is positive feedback?
-System deviates from optimum
-Change is detected by the receptor
-A change is then produced which causes an even greater deviation from the optimum
How are endocrine glands and hormones linked?
-Hormones are organic chemicals produced in an endocrine gland
-They travel in the blood and can be widespread or targeted
-Protein or peptide hormones e.g. insulin, ADH
-Steroid hormones e.g. oestrogen, progesterone
What are the glands?
-Hypothalamus
-Pituitary gland
-Thyroid gland
-Pancreas
-Parathyroid gland
-Adrenal gland
-Kidneys
-Ovaries
-Testes
How are hormones released?
Can be stimulated to release hormones by both nerves or other hormones
What is the link between the pituitary gland and the hypothalamus?
-Both located in the brain
-The hypothalamus often controls the pituitary gland
What is the pituitary gland?
-Controlled by the hypothalamus
-Produces 6 hormones from the anterior lobe
-Produces 2 from the posterior lobe
What is the thyroid stimulating hormone?
Controls the secretion of thyroxin from the thyroid gland
What is oxytocin hormone?
Stimulates the muscles of the uterus to contract during labour and stimulates the contraction of cells in the mammary tissue to release milk
What is antiduretic hormone (ADH)?
Decreases the urine volume and causes arteries to constrict after haemorrhage
What is prolactin hormone?
Stimulates and maintains the production of milk by mammary glands
What is the lutinising hormone (LH)?
Stimulates ovulation and formation of corpus luteum and prepares the uterus for implantation in females and stimulates the testes to produce testosterone
What is follicle stimulating hormone (FSH)?
Stimulates ovaries to produce oestrogen and stimulates the development of ova in females and stimulates the testes to produce sperm in males
What is ACTH hormone?
Controls the secretion of some hormones of the adrenal glands
What is the growth hormone (GH)?
Stimulates the growth of body cells and increases the build up of proteins
What happens in the pituitary gland and hypothalamus?
-Hypothalamus contains neurosecretory cells which produce secretions from the axons
-Cells 1 (group of neurosecretory cells) produce substances that stimulate or inhibit the release of hormones from the anterior pituitary
-They are known as releasing factors (if they stimulate) or release-inhibiting factors (if they inhibit)
-Neurosecretory cells 2 produce secretions that are stored in the posterior pituitary and released later as hormones
What is a second messenger?
-Hormones bind to a receptor on the target cell membrane
-Triggers a series of intracellular membrane bound reactions
-Stimulates the release of a second messenger
-The second messenger activates enzymes to alter the metabolism of the cell
What is the example of a second messenger (adrenaline)?
-Adrenaline binds to a receptor
-This activates an enzyme called adenyl cyclase which converts ATP to cyclic AMP (cAMP)
-cAMP acts as a second messenger
-Triggers different responses in the cell e.g. increased respiration and muscle contraction
What is oestrogen?
-A steroid hormone that can affect transcription by binding to a transcription factor
-Transcription factor is known as an oestrogen receptor
-Bind together to form an oestrogen to oestrogen receptor complex
-Moves to the nucleus where it binds to the promoter region before the target gene
-It then acts as a promoter
What is an oestrogen receptor?
-A transcription factor
-It regulates gene expression events that culminate in cell division
-Important for mammary gland development
How do hormones enter the cell?
-Pass through the membrane and bind to a receptor inside the cell
-They form a hormone receptor complex which passes through into the nucleus and acts as a transcription factor to regulate gene expression