Homeostatis Flashcards

1
Q

Coordinator

A

Formulates a response to a stimulus

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2
Q

Effector

A

Muscle or gland that produces the response

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3
Q

Homeostatis

A

The maintenance of a stable internal envrionment

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4
Q

Negative feedback

A

When there is an increase/decrease from set point opposite effect is instigated
Producing a response that returns the value to the norm

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5
Q

Positive feedback

A

Occurs when a deviation from an optimum causes greater deviation from the normal

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6
Q

Thermoregulation

A

Regulation of body temperature

If body temp to low lack of Ke so slower enzyme controlled reactions less successful collisions and less esc formed per second

If body temp to high enzymes denature (breaking of hydrogen and ionic bonds in 3* between R groups)

If blood pH changes enzymes+ other proteins denature
(Hb antibodies plasma proteins)

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7
Q

Endotherms + examples

A

Mammals+ some birds+ fish

Maintain body temp through physiological and behavioural means

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8
Q

Ectotherms + examples

A

All other animals (reptiles,amphibians)

Maintain body temp through behavioural means only such as
Exposing themselves to the sun
Taking shelter
Gaining warm from the ground

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9
Q

What is low levels of glucose known as

A

Hypoglycaemia

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10
Q

High levels of glucose known as

A

Hyperglycaemia

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11
Q

What is insulin secreted by And where
Describe Process to

A

Secretes by beta cells in the pancreas
Reduces blood glucose levels

Insulin binds to complementary receptors on target cells
Controls the uptake of glucose carrier proteins of target cells
(Striated muscle+ adipose tissue)

Insulin activates enzymes which converts glucose to glycogen (glycogenesis) reducing blood glucose

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12
Q

What is glucagon secreted by and where
Process to

A

Glucagon secreted by alpha cells in the pancreas

Glucagon binds to complementary receptors on target cells
Activates enzymes which hydrolyse glycogen into glucose (glycogenolysis)

Activates enzymes which convert glycerol and amino acids into glucose (gluconeogenesis

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13
Q

Describe the role of glycogen formation and its role in lowering blood glucose levels

A

Glucose concentration in liver falls
Higher concentration in the blood
Glucose concentration gradient creates
Glucose leaves the blood by facilitated diffusion via channel protein

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14
Q

What is adrenaline secretes by
What does it do

A

Secretes by adrenal glands (above kidney)
Increases blood glucose levels

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15
Q

Second messenger mode

A

Adrenaline+glucagon both bind to specifically complementary transmembrane protein receptors of target cells - first messenger

Hormone-receptor complex formed (receptor 3* shape changes)
Activates adenylate cyclase which converts atp into cAMP
cAMP activates protein kinase which hydrolyses glycogen into glucose
So gluconeogenesis occurs

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16
Q

Factors affecting blood glucose concentration

A

Diet- glucose from hydrolysis of starch,maltose,sucrose,lactose

Glycogenolysis

Gluconeogeneis

17
Q

Type 1 diabetes

A

Insulin dependent diabetes

Insulin deficiency due to autoimmune killing of beta cells
(Due to virus or faulty gene)

18
Q

Type 2 diabetes

A

Non-insulin-dependent diabetes

Insulin produced but insulin receptors on target cells are unresponsive so insulin has no effect

19
Q

Symptoms of diabetes

A

High thirst due to osmosis of water from cells to the blood which has a low water potential

Large volumes of urine production due to excess water in blood

Poor vision due to osmotic loss of water from eye lens

Tiredness due to loss of glucose in urine and poir uptake of glucose by liver and muscle cels

20
Q

How is urea from the blood

A

High hydrostatic pressure
Causes ultrafiltration at glomeruli
Through basement membrane
Enabled by small size of urea molecule

21
Q

Describe how ultrafiltration produces glomerular filtrate

A

Higher than normal hydrostatic pressure
Glucose,urea mineral ions
Pass through basement membrane
Protein too large to go through
Presence of podocytes
Presence of pores

22
Q

How is the high hydrostatic pressure in the glomerulus produced

A

Afferent arteriole is wider in diameter than the efferent arteriole that exists
Causing high hydrostatic pressure