Homologues, orthologues, and paraolgues Flashcards
1
Q
Homologues
A
Are regions of genomes. or portions of proteins, that are derived from a common ancestor. Because only in rare cases can we actually observe the ancestor-descendant relationship, most assignments of homology are inferences from similarity in sequence, structure, and/ or genomic context.
2
Q
Paralogues
A
Are related genes that have diverged to provide separate functions in the same species
-ex. alpha and beta-chains of human haemoglobin
3
Q
Orthologues
A
Are homologues that perform the same function in different species
-ex. human and horse myoglobin