Hormonal Communication Flashcards
(12 cards)
What are Hormones?
Chemical messengers which travel in the blood secreted from endocrine glands
What is a steroid hormone?
Lipid soluble
Pass through SCM and bind to receptor in cytoplasms
How to steroid hormones work?
H-R complex acts as an transcription factor or inhibitor
What is a non-steroid hormone?
Non-lipid soluble
Initiate response to receptor on CSM cause secondary cellular messenger release
What are the exocrine functions of the pancreas?
Produce emzymes and pancreatic juices which are secreted into duodenum by acinar cells. (Amylase, trypsinogen and lipase)
What are the endocrine function of the pancreas?
Islets of langerhans
α cells- secrete glucagon
β cells- secrete insulin
Lots of capillaries
What should you control blood glucose?
Can effect WP on blood and tissue fluid
Required for respiration
Use in the manufacture of cellular products
How does blood glucose conc change?
Increase after carb meal
Decrease after fasting and exercise
What enzyme is used in hepatocytes when blood glucose low ?
Andenyl Cyclase which convert ATP to Camp
What happens when blood glucose is too low?
Detected by α cells which secrete glycogen
Target Hepatocytes
Bind to receptor in membrane
Activate Andenyl Cyclase which converts ATP to Camp
Causes a cascade reaction
Glycogen converted to glucose
Fats + aa converted to glucose
What happens when blood glucose is too high?
Insulin secreted travels through circulatory system to target (Liver)
Binds to glycogen receptor
Activates trypsin kinase emzyme which cause activation of emzymes
Vesicles with glucose transporter fuse to membrane (exocytosis)
More glucose taken in, glycogenisis
More used in respiration
What’s the emzyme called thats in hepatocytes for high blood glucose?
Tyrosine Kinase emzyme
