hormone presentation functions Flashcards
(15 cards)
anti-inflammatory, tissue remodeling, treats fibrosis in different organs, airway remodeling, pregnancy and labor facilitation
relaxin
cell proliferation/division, involved in the integumentary system, treats diabetic foot ulcers, wound healing, reduces inflammation, treats atopic dermatitis, maintains CT
epidermal growth factor
regulates mood, behavior, sleep cycles, and appetite
regulates human brown adipose tissue (BAT) function, modulates food seeking behaviors through the olfactory pathway, increases symptoms of diarrhea
serotonin
sleep/wake states, loss of these neurons can lead to narcolepsy, maintains wakefullness, feeding behaviors, energy homeostasis, reward systems, cognition/mood, improves spatial learning and memory
orexin/hypocretin
satiety, circadian rhythm regulation, thermoregulation, anxiety stress and fear, gastrin production, immune response, male sexual functions, over expression can lead to cancers
bombesin
production and maintenence of RBCs, protects nervous system, kidneys, and heart from tissue damage/ischemia, creation of new blood vessels and nerve cells, reduces high blood sugar, slows development of retinopathy, encoding of glycolytic enzymes, angiogenic factors, proteins involved in iron uptake, hemoglobin synthesis
erythropoietin
promotes glucose release from hepatocytes (activates PkA), stimulates appetite, high levels –> obesity, pancreatic inflammation (type two diabetes), increase sperm motility
asprosin
bind to opioid receptors in spinal cord to inhibit pain signals from reaching the brain
release dopamine to create a euphoric effect
aids in circadian rhythm
endorphins
better mineral to matrix ratio, better bone material quality, increases beta cell production –> lower glucose, reduces fat storage (adipocyte death and lower lipid content), increases testosterone production, activates neurotransmitter synthesis related to memory and learning
osteocalcin
increased gastric motility and gastric emptying, stimulation of migrating motor complex (MMC), increases pepsin release, stimulates secretion of bile, increases esophageal pressure, stimulates appetite, increases arterial relaxation
motilin
appetite regulation, increases BP and atherosclerosis, involved in puberty onset (release of FSH and LH), proliferation of immune cells, production of pro-inflammatory cytokines, stimulates osteoblasts, triggers the sympathetic nervous system to increase heart rate, resistance leads to obesity
leptin
protects cardiomyocytes from hypoxia and promotes proliferation after an MI, treats pulmonary tuberculosis and diabetes
stimulates T-cell production and increased immune function
has anti-tumor effects
thymosin
involved in food uptake regulation, modulation of pituitary hormone release
involved in opioid-independent antinociception serves as a modulator for neurotransmitter systems (such as dopaminergic, cholinergic, glutamatergic, etc).
affects synthesis of hormones from the AP (CRH, GnRH, GHRH, TRH, prolactin)
neurotensin
synchronizes internal biological clock to the light/dark cycle
melatonin
stimulates GH release, suppresses insulin release, maintains cardiac output and BP, reduces myocardial fibrosis after an MI
ghrelin
