Hormones

Question 1

What is a hormone?

Answer 1

regulatory biochemical from endo glands or nerves -> systemic circulation -> affect target tissue receptors.
May -> new products or hormones
Can be peptides, proteins, steroids
Initiate feedback mechanisms

Question 2

Hormone mode of action…

Answer 2

minute amounts
short half lives
longer lasting effects than nerves

Question 3

Describe Ferguson’s reflex (draw)… what kind of response is involved?

Answer 3

slide 8…

Question 4

GnRH is considered a …?

Answer 4

driver

Question 5

FSH is considered a …?

Answer 5

stimulator

Question 6

LH is considered a …?

Answer 6

ovulator

Question 7

E2 is considered a …?

Answer 7

receptor

Question 8

P4 is considered a …?

Answer 8

regulator

Question 9

PG is considered a …?

Answer 9

terminator

Question 10

Hormones from the brain…

Answer 10

melatonin, kisspeptin, prolactin, opioids

Question 11

Hormones from the hypothalamus…

Answer 11

GnRH

Question 12

Hormones from the pituitary…

Answer 12

FSH

LH

Question 13

Hormones from the ovary…

Answer 13

Follicle (E2)

CL (P4)

Question 14

Hormones from the uterus…

Answer 14

PGF2alpha

Question 15

What are the gonadal hormones?

Answer 15

T4, E2, prog., inhibin, activin, AMH…

Question 16

Steroid/gonadal hormone prod… chol -> oestradiol…? (remember AG’s flow chart)

Answer 16

chol -> preg off to prog OR preg -> testosterone -> oestradiol via aromatase

Question 17

Placenta produces which hormones?

Answer 17

progestogens
relaxin
others…

Question 18

Draw clinical summary slide & explain…

Answer 18

slide 20…

Question 19

FSH does what exactly? LH does what exactly? (female)

Answer 19

FSH stimulates follicle dev. thru to antral stage then LH takes follicles thru to maturity & ovulation then lutenises Granulosa & theca intern cells to become Luteal cells

Question 20

FSH does what exactly? LH does what exactly? (male)

Answer 20

FSH -> Sertoli cells -> E2 -> spermatogenesis, LH -> T4 -> libido & effects on spermatogenesis

Question 21

Steriod hormones…

Answer 21

E2, Prog., T

Question 22

GnRH is a … hormone?

Answer 22

decapeptide

Question 23

FSH & LH are … hormones?

Answer 23

glycoprotein

Question 24

Prolactin is a … hormone?

Answer 24

protein

Question 25

Oxytocin is a .... hormone?

Answer 25

octapeptide

Question 26

inhibin & activin are .... hormones? (as are hCG & eCG)

Answer 26

glycoproteins

Question 27

Protein hormone action (draw)

Answer 27

slide 36

Question 28

Steroid hormone action (draw)

Answer 28

slide 38 (attach to water soluble molecule -> longer half live)

Question 29

What are some factors affecting hormonal action?

Answer 29

pattern & duration of secretion half life of hormone receptor density receptor-hormone affinity

Question 30

Detection methods of hormones...

Answer 30

ELISA | RIA

Question 31

Feedback mechanisms in males...

Answer 31

draw (slide near end of hormone lec)