Hormones and Electrolytes Flashcards Preview

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Flashcards in Hormones and Electrolytes Deck (12):
1

Angiotensin II

-synthesized in response to dec. BP
-causes efferent arteriole constriction
-preservation of renal function (FF) in low volume state with simultaneous Na reabsorption to maintain circulating volume

2

Atrial Natriuretic Peptide (ANP)

-secreted in response to inc. atrial pressure
-causes inc GFR and inc. Na filtration with no compensatory Na reabsorption in distal nephron
-net effect: Na loss and volume loss

3

Parathyroid Hormone

-secreted in response to dec. plasma Ca, inc. plasma PO4, or dec. plasma 1-25 D3
-causes inc. Ca reabsorption, dec. PO4 reabsorption, and inc. 1-25 D3 production

4

Aldosterone

-secreted in response to dec. blood volume and inc plasma K
-causes inc. Na reabsorption, K secretion, inc. H secretion

5

ADH (vasopressin)

-secreted in response to inc. plasma osmolarity and dec. blood volume
-causes inc. number aquaporins and inc. H2O reabsorption

6

Things That Shift K Out of Cell (causing hyperkalemia)
-DO LABS

-Digitalis (blocks Na/K ATPase)
-hyperOsmolarity
-Lysis of cells (crush injury, rhabdomyolysis, cancer)
-Acidosis
-Beta blockers
-high blood Sugar (insulin deficiency)

7

Things That Shift K Into Cell (causing hypokalemia)

-hypo-osmolarity
-alkalosis
-beta adrenergic agnoist (inc. Na/K ATPase)
-insulin (inc. Na/K ATPase)

8

Effect of High Serum K

-wide QRS
-peaked T waves
-arrythmias (cardiac arrest)
-muscle weakness

9

Oval Fat Body Casts

-sign of nephrotic syndrome

10

Diffuse

>50% glomeruli involved

11

Nephritic Syndromes

-acute post infectious glomerulonephritis
-rapidly progressive (crescentic) glomerulonephritis (RPGN)
-diffuse proliferative glomerulonephritis (DPGN)
-IgA nephropathy (berger disease)
-alport syndrome
-membranoproliferative GN

12

Nephrotic Syndromes

-focal segmental glomerulosclerosis
-minimal change disease
-membranous nephropathy
-amyloidosis
-diabetic GN