htn Flashcards

(64 cards)

1
Q

hypertension more common in ___ and ____ pts

hint **race, and gender

A

male, and black

more severe among black patients

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2
Q

pathogenesis of htn?

A

bp reacts to change in enviornemnt

primary factors= RAAS, and sympathetic nervous system

multifactorial, not well understood

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3
Q

risk factors for primary hypertension

A

age
obesity
family history
race
high sodium
physical inactivity
excess alcohol

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4
Q

secondary HTN is __ causes such as

A

specific,

meds, nsaids
renal artery stenosis
illicit drugs such as meth or cocaine
aldosteronism
obstructive sleep apnea

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5
Q

what is renal artery stenosis and who is it seen in

A

older pt with hypertension

young adult women with fibromuscular dysplasia

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6
Q

when to suspect secondary hypertension cause

A

resistant to three or more drugs

family history

less than 30 years old

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7
Q

renal artery stenosis signs

A

epigastric or renal artery bruits

severe htn in pt over 55

increase in serum creatinine, at least 50% after administering ace or arb, do to reduced blood flow to the area

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8
Q

diagnosis of renal artery stenosis

A

renal angiography

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9
Q

renal artery stenosis tx

A

ace or arb

if recurrent flash pulmonary edema, or intolerant to medical therapy should consider revascularization

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10
Q

htn is risk factors for what complication

A

coronary artery disease
aortic dissection
aortic abdominal aneurysm
heart failure
left ventricular hypertrophy
STROKE** (ischemic and hemorrhagic)
kidney disease, can be a cause and/or target
atherosclerotic disease

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11
Q

hypertension is the most common AND IMPORTANT risk fatcopr for what?

A

ischemic and hemorrhagic stroke

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12
Q

secondary cause of aldosteronism; triad, lab work, and treatment

A

hypertension usually >150/100, hypokalemia and alkalosis

need to check plasma aldosterone concentration
PAC ratio: PRC is positive

can either be Surgical or medical
- excision
spironolactone, and low salt

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13
Q

what is primary aldosteronism and why is it a secondary cause of hypertension

A

increase in aldosterone leads to increase in sodium retention

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14
Q

cushings as a cause of secondary htn features

lab work

A

obesity, easy bruising, lethargy, moon face,

24 hour cortisol excretion

low dose dexamethasone suppressipn test

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15
Q

most patient with htn die from complications of _______

A

atherosclerosis

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16
Q

in preparation for taking a blood pressure reading what will you do prior?

A

make sure patient has emptied bladder first*

have the patient relax in a sitting or lying position for at least 5 minutes before

patient should avoid caffeine or alcohol for at least 30 minutes before

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17
Q

checking blood pressure reading for the first office properly requires checking only 1 arm, true or false?

A

false,

must check 2 arms
use the arm with the higher reading for subsequent blood pressure reading

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18
Q

on first visit with your patient how will you check blood pressure?

A

will check blood pressure in both arms

will use arm with higher reading for subsequent reading

wait 1-2 minutes between readings

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19
Q

in auscultating bp, the first (1st) korotkoff sound is the _____ bp whereas the diassapearence of korotkoff sounds is the ______ bp

A

systolic bp

diastolic bp

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20
Q

to estimate level of bp you will average readings use an estimate of ____ bp and on ____ occasions

A

2 or more blood pressure reading
on
2 or more occasions

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21
Q

preferred method to confirm diagnosis of htn

A

at home, interval
15- 20 mins daytime intervals
30-60 minutes during night/sleep

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22
Q

measuring at home bp best to assess for _______syndrome

A

white coat

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23
Q

most common symptom in pts with hypertension,

A

headache

most patients are asymptomatic

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24
Q

best way to diagnose htn is through _____ bp reading

A

multiple
>2 readings on >2 occasions

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25
if assessing/considering HTN what should be included in the physical exam ?
general appearence/vitals cardiac exam - assess for heaves - auscultate the heart check extremities - assess for edema (CHF) HEENT, fundoscopic for hypertensive look for cotton wool spots, AV knicking neuro exam, - any headache, confusion and visual disturbances
26
you see increase in creatinine greater than 50% after starting an ace or an arb and hear bruit epigastric what are u suspecting is causing this?
renal artery stenosis
27
signs like bradycardia, anfd tachycardia, cold intolerance, and absent period are suggesting of what secondary condition?
thyroid
28
HTN treatment in all patients involves including what?
lifestyle modification pharmacological , multiple medication
29
lifestyle modification
wt reduction DASH diet sodium reduction physical activity moderate alcohol consumption other smoke cessation
30
JNC8 guideline for monotherapy tx (general population, no diabetics or ckd)
non black, any of the 4 classes - thiazide - ccb - ace - arb black- thiazide or ccb age if >60 bp >150/90 (initiate) if <60 bp >140/90 initiate pharmacotherapy
31
African American Pt has a Bp of 145/98 and has history of ckd is present with/ without diabetes initiate, what meds? JNC8
ace or arb ALL patients if bp >140/90
32
for diabetes, no CKD, jnc 8 guideline
non black= any of the 4 classes (thiazide, ccb, ace, or arb) black+thiazide, or ccb initiate pharmacological therapy if bp >140/90 all ages
33
combination therapy jnc8 guideline
used when systolic bp is greater than (>160) and diastolic is greater than 100 or 20/10 above goal can select 2 drug classes from the main class of antihypertensives (thiazide, ccb, ace/arb)
34
a pt who is 70 years old, no diabetes or kidney disease, on an ace currently with a bp of 170/110, using jnc 8 guidelines how to precede
COMBINATION therapy use thiazide, and ace can do arb and thiazide typically its an ace or arb with a thiazide or ccb
35
goals for treatment in pt with ckd or dm is _____ (jnc8)
<140/90
36
in the general population (>60) jnc 8 guidelines BP goal is
<150/90
37
general pop <60 jnc 8 guidelines bp goal is
<140/90
38
other treatment in cases of migraine, and hyperthyroidism
migraine, beta blocker hyperthyroidism= beta blocker
39
comorbid conditions and adverse effects with antihypertensive classes 1. depression 2. gout 3. hyperkalemia
1. depression- beta blockers 2. diuretics (no diuretics, for gout, can increase uric acid) 3. ace or arb (Discontinue briefly, for hyperkalemia)
40
how often to follow up when initiating therapy (jnc)
monthly follow up
41
if goal is not reached if goal bp still not reached with 3 meds, can add 4th med and ________
refer to a specialist
42
ACC/AHA hypertension threshold
normal bp= systolic <120 and diastolic <80 elevated 120-129 <80 stage 1= 130-139 mmHg OR 80-89 mmHg stage 2= >140 >90
43
stage 1 acc/aha htn tx
10 yr ASCVD risk >10%, monotherapy with diuretic, ccbs, ace, and arb if 10 year is <10% non pharmacological tx
44
if stage 2 htn use __ agents from __ different classes
2 from 2 different classes 2 avoid ace and arb
45
sotalol is a beta blocker that is used for what?
used as an antiarythmic agent, used in atrial fibrillation, and ventricular arrhythmia
46
tamulosin, alfuzosin is a ____ blocker which is used in management of what condition
alpha 1 used for benign prostatic hypertrophy
47
128/94 using acc/ahs guidelines how will you treat
use 2 antihypertensives meds, and additional lifestyle factors Stage 2 Systolic >140 Diastolic >90
48
if bp is 120/85, what stage and how to tx acc guideline
stage 1 if >10 yr risk add 1 hypertensove med
49
stage 1 acc
130-139 OR 80-89
50
if 60 year old patient, and ckd, what is goal bp, according to JNC 8
<140/90
51
pt bp is 135/75 what stage
stage 1 130-139 or if 80-89
52
using acc guideline, a 49 y/o white pt with bp of 139/65, 10 year risk is 11% and past medical history is gout, and DM how do u want to txt the pt?
arb or ace ccb no diuretic if black only can do ccb
53
if pt has hypokalemia what diuretic, potassium sparing diuretic
triampterie, potassium sparing diuretic
54
68 y/o black patient with a reading of 138/78 and ascvd at 14% with PMH of ckd how do u tx acc guideline
138/78= stage 1 130-139 black would normally do thiazide or diuretic but ckd means he needs ace and arb
55
dilt and verampiril other use for non dihydro
svt, afib
56
non dihydro adverse
bradykinin constipation
57
hypertensive emergency criteria bp range what organs can be targeted
systolic is over 180 diastolic is over 120 htn encephalopathy, acute ischemic stroke
58
what would you do in hypertensive emergency? what is the goal
treat with Iv hypertensives
59
in hypertensive emergency, your goal is to reduce bp by ___ in the first hour and then to 160/100 in ___HOURS , then normal over next 24 hours,
25% 2-6
60
EXCEPTIONS TO HTN EMERGENCY REDUCTION BY 25% THEN TO 160/100 INCLUDE
AORTIC DISSECTION, LEBATOLOL TARGET >120, >80 ISCHEMIC STROKE, FIRST LINE= NICARDIPINE. AND LEBATOLOL BP LOWERED IF >185/110 IN THROMBOLYSIS PTS IN FIRST LINE NOT LIWERED UNLESS 220/120 NOT CANDIDATE
61
HYPERTENSIVE URGENCY
SYSTOLIC >180 DIASTOLIC >120 NO SIGNS OF ORGAN FAILURE | CAN BE OVER DAYS
62
RESISTANT BP
CONTROLLED BUT ON OVER 4 MEDS ON OVER 3 MEDS BUT NOT WELL CONTROLLED
63
If pt is over 65 Bp is 145/90 do u initiate pharmacological management for tx of hypertension ? Using inc 8
No systolic needs to be greater than 150 in order to start treatment for hypertension
64
If pt with pmh of diabetes being treated with an ace, for mono therapy Bp with mono therapy is at 160/ 100 what would u want to do now ? Using JNC 8 guidelines
Now would like to do combination therapy, combinging ace and now do thiazide