HTN Flashcards

(40 cards)

1
Q

What is MAP?

A

Mean Arterial Pressure = Cardiac output (stroke volume x heart rate) x Arterial Pressure (length of vessel x viscosity / radius^4)

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2
Q

What MAP is regulated by?

A

sympathetic nervous system
RAAS system
Renal function
Hormones: epinephrine, vasopressin, angiotensin II

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3
Q

What is a sphygmomanometer?

A

to measure BP

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4
Q

What are the modifiable risk factors of hypertension?

A
  • smoking
  • sedentary lifestyle
  • abdominal obesity, insulin resistance
  • excess sodium intake
  • poor diet quality
  • stress
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5
Q

What are the non-modifiable risk factors of hypertension?

A
  • age (> 60 yo)
  • men, postmenopausal women, ethnicity
  • family history
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6
Q

How does smoking affect BP?

A

by interfering with nitric oxide which is a compound that helps vasodilatation => smoking = vasoconstriction

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7
Q

How does renal disease affect BP?

A

decrease blood results in a release of angiotensin II => water retention, vasoconstriction, Na+, Cl- => blood volume

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8
Q

What are the ACC related to hypertension?

A
  • Cardiovascular Disease
    HF, LV hypertrophy or dysfunction, MI
  • Cerebrovascular
    Stroke. TIA, Hemorrhage, Dementia (rupture of blood vessels in brain)
  • Retinopathy
  • Peripheral artery disease
  • Nephropathy
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9
Q

What are the levels of stratifying risk from the highest to lowest?

A
  • High-risk patient
  • DM
  • Moderate-to-high risk
  • Low risk
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10
Q

What classifies a patient at high risk?

A
  • renal disease
  • CVD
  • over 75 yo
  • 10 years global cardiovascular risk > 15%
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11
Q

What is the BP threshold for people with diabetes?

A

130/80

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12
Q

What are the treatment goals of hypertension?

A
  • reduce risks of CVD and renal disease

- reduce BP to normal range

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13
Q

What does the plan for hypertension include?

A
  • PA
  • Weight loss
  • Nutrition therapy
  • Alcohol, smoking, relaxation therapy
  • Medication
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14
Q

What is the impact of sodium intake on BP?

A

high Na excretion (intake) = high BP

lowering Na intake results in decrease of SBP

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15
Q

What are the diet contributors to BP?

A
  • Na
  • K
  • Mg
  • Ca
  • EtOH
  • excess weight, obesity, high calories
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16
Q

What was the finding with the study comparing the BP of US diet vs DASH diet?

A

if eating an unhealthy diet = more significant decrease in BP to a lower Na intake

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17
Q

True or false

K + supp is not recommended to prevent hypertension in normotensive people

18
Q

TRUE or FALSE

Supp above the recommended intake of K can treat HTN?

19
Q

TRUE or FALSE

High-intensity PA have more benefits for HTN than moderate PA in + to daily activities

20
Q

TRUE or FALSE
B-blockers are recommended as the first trt for ppl over 60 yo
explain

A

false

because elderly have a lower adrenergic response

21
Q

What are the possible SPC?

A

ACE-1 + ARB/CCB

Diuretic + ACE-1/ARB

22
Q

What is to avoid when taking HTN drugs?

A

avoid licorice

CCB: no grapefruit, limit alcohol and coffee

23
Q

What are the treatment goals in most ppl and diabetic ppl?

A

SBP < 140, DBP < 90

DM : SBP < 130, DBP < 80

24
Q

What are the contributing factors to hypertension?

A
excessive vasopressin and angiotensin II
smoking
renal disease
adrenal disorders
hyperinsulinemia 
neurological diseases
25
What are the threshold and targets for anti hypertensive therapy?
High risk patients >130 to <120 DM >130/>80to <130/<80 Moderate risk >140/>90 to <140/<90 Low risk >160/>100 to <140/<90
26
What are the 3 sodium controlled diets?
3000 mg Na 2000 limit milk and milk products 1000 limit bread
27
What are the K mechanism to regulate blood pressure?
``` natriuresis (increase Na excretion) suppressed renin vasodilation may reduce sympathetic activity and angiotensin II protects against familial susceptibility ```
28
What is the correlation btw calcium and HTN?
calcium decrease BP Na excretion increase nitric oxide action decrease super oxyde and prostanoids no supp
29
What is the correlation btw magnesium and HTN?
inverse effect
30
what is the effect of alcohol on BP?
increases BP on long term increases Ca intake by cells = vasoconstriction SNS cortisol secretion
31
What are the nutrition information that can be use to diagnose HTN?
``` high fat diet or inadequate fat intake excessive energy intake excessive sodium low fiber, Ca, Mg, K overweight/obesity physical inactivity food and nutrition knowledge deficit ```
32
What is the order of drug prescription for HTN?
diuretics, ACE, ARB, CCB, B-blockers, SPC
33
What is spirilolactone?
potassium-sparing diuretic
34
What are thiazides?
diuretics
35
What is triamterene?
potassium sparing diuretic = blocks aldosterone
36
what is amiloride?
K sparing diuretics
37
what is ramipril?
ACE inhibitor = blocks the conversion of angiotensin I to angiotensin II = no aldosterone, vasodilatation, decreased vasopressin = decreased BP
38
what are valsartan and losartan?
ARB same effects as ACE
39
what is amlodipine?
CCB
40
what are metoprolol, propranolol, atenolol?
B-blockers = decreased cardiac output and HR