Hyperlipidemia Drugs Flashcards

1
Q

What are Statins used for?

A

Decrease LDL, stroke prevention

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2
Q

What is the action of Statins?

A

Inhibit hepatic synthesis

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3
Q

What are the side effects of Statins?

A

GI issues, rash, headache, myalgia

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4
Q

What is a contraindication of Statins?

A

Pregnancy- category X

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5
Q

What are Bile Acid Sequestrates used for?

A

Decrease LDL

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6
Q

What is the action of bile acid sequestrates?

A

Prevent cholesterol absorption

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7
Q

What are the side effects of bile acid sequestrates?

A

GI issues, abdominal fullness, flatulence, constipation

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8
Q

What are Fibrates used for?

A

Decrease HDL and high triglycerides

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9
Q

What is the action of Fibrates?

A

Decrease hepatic function

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10
Q

What are the side effects of Fibrates?

A

Gallstones, diarrhea, epigastric pain, dyspepsia

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11
Q

Who should avoid Fibrates?

A

Patients with kidney and liver disease

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12
Q

What is Niacin used for?

A

Decreasing LDL, high triglycerides

Increasing HDL

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13
Q

What is the action of Niacin?

A

Inhibit free fatty acids

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14
Q

What are the side effects of Niacin?

A

Skin flushing, pruritus, hepatotoxicity

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15
Q

What is Niacin contraindicated in?

A

Liver disease

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16
Q

What are Cholesterol Inhibitors used for?

A

Decrease LDL, triglycerides

Increase HDL

17
Q

What is the action of Cholesterol Inhibitors?

A

Inhibit cholesterol

18
Q

What are the side effects of Cholesterol Inhibitors?

A

Cholecystitis, gallstones, nausea

19
Q

What is contraindicated with the use of cholesterol inhibitors?

A

Liver disease and the use of fibrates