hypersensitivity Flashcards

1
Q

which antibody drives the reaction in the baby for haemolytic anaemia

A

IgG

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2
Q

what does the combs test detect

A

antibodies to red blood cells

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3
Q

How does the direct combs test work

A

uses baby’s blood to demonstrate the presence of antibodies attached to red blood cells.

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4
Q

How does the INdirect combs test work

A

uses mothers serum to demonstrate the presence of antibodies that are capable of binding to RBCs

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5
Q

RA is a type of which hypersensitivity reaction

A

type 3 immune complexes

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6
Q

what are the autoantibodies in RA

A

rheumatoid factor

anti cyclic citrullinated peptide

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7
Q

Graves disease pathogenesis

A

antibody to TSH receptor

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8
Q

which cell type is responsible for initial response in sensitisation phase of allergy development upon first exposure to allergen

A

APC

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9
Q

which cell type is responsible for initial response in effector phase upon re exposure to allergen

A

memory B cell

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