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Hypersensitivity Flashcards

1
Q

These are environmental antigens that typically elicits allergic responses in susceptible individuals

A

Allergens

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2
Q

What are the AEROALLERGENS?

A

Pollens
Mold Spores
Animal Dander
Fecal material excreted by mites
Cockroaches

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3
Q

Clinically adverse reflecting acquired immune response that are marked PHENOTYPICALLY.

A

Allergy

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4
Q

It is an acute, generalized allergic reaction with simultaneous involvement of several organ systems, usually CARDIOVASCULAR, RESPIRATORY, CUTANEOUS, AND GASTROINTESTINAL.

A

Anaphylaxis

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5
Q

Ana:_____;Phylaxis:_____

A

Ana: Opposite
Phylaxis: Protection

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6
Q

refers to Anaphylaxis in which HYPOTENSION, with or without loss of consciousness.

A

Anaphylactic shock

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7
Q

It is a condition in which the symptoms and signs of anaphylaxis occur in the ABSENCE OF AN ALLERGEN-ANTIBODY MECHANISM.

A

Anaphylactoid Reaction

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8
Q

another term for allergy

A

Atopy

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9
Q

In Atopy, a word meaning “strange disease” derived from the Greek for “_______”.

A

out of place

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10
Q

____ of activated mast cells, basophils, and eosinophils release preformed primary mediators.

A

Degranulation

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11
Q

In Degranulation, What are the preformed primary mediators?

A

Heparin
Histamine
Protease
Eosinophil chemotactic factor
Neutrophil chemotactic factor

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12
Q

is a process of temporarily supressing immediate HYPERSENSITIVITY reactions by repeated injections of increasing amounts of the offending allergens

A

Desensitization

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13
Q

can be defined as a NORMAL but EXAGGERATED/UNCONTROLLED immune response go an antigen that can produce inflammation,. cell destruction, or tissue injury.

A

Hypersensitivity

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14
Q

It is the basis of ACUTE ALLERGIC REACTIONS caused by molecules released by mast cells when an allergen interacts with membrane-bound IgE.

A

Immediate Hypersensitivity

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15
Q

It is often used synonymously with the term cell-mediated immunity

A

Delayed Hypersensitivity

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16
Q

a PRIMARY immune response to an antigen and has no clinical consequences

A

Sensitization stage

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17
Q

A SECONDARY immune response that id deleterious to the individual.

A

Effector Stage

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18
Q

Distinguish Humoral hypersensitivities from cellular hypersensitivities

A

Older classification

19
Q

Characteristic :(Response time following challenge dose of antigen)

“Gradually rises to peak at 24-72hrs”

A

Delayed Hypersensitivity

20
Q

Characteristic :(Responsible cellular and chemical agents)
“ B cell product”

A

Immediate Hypersensitivity

21
Q

Characteristic :(Response time following challenge dose of antigen)

“Visible within minutes; diminished within few hours”

A

Immediate Hypersensitivity

22
Q

Characteristic :(Responsible cellular and chemical agents)

“T cell product”

A

Delayed Hypersensitivity

23
Q

Characteristic: (Passive transfer via)

“SERUM”

A

Immediate hypersensitivity

24
Q

Characteristic: (Passive transfer via)

“T Lymphocytes”

A

Delayed Hypersensitivity

25
Q

Characteristic: (Chemotherapy)

“Steroids”

A

Delayed Hypersensitivity

26
Q

Characteristic: (Chemotherapy)

“Antihistamine and Adrenergenic compounds”

A

Immediate Hypersensitivity

27
Q

Characteristic :(Target tissues)

“Primarily smooth muscles; organs; vascular tissue”

A

Immediate Hypersensitivity

28
Q

Characteristic:(Target tissue)

“No special targets; generalized response”

A

Delayed Hypersensitivity

29
Q

Characteristic:(Histology of skin response)

“Erythema, Edema, and Wheal Formation; granulocytes predominate in early response; mononuclear cells increase in later response”

A

Immediate Hypersensitivity

30
Q

Characteristic:(Histology of skin response)

“Erythema and Induration; little edema; no wheal; mononuclear cells predominate”

A

Delayed Hypersensitivity

31
Q

Characteristic:(Tissue Death)

“Common”

A

Immediate Hypersensitivity

32
Q

Characteristic:(Tissue Death)

“Uncommon”

A

Delayed Hypersensitivity

33
Q

Characteristic:(Relative ease of desensitization)

“Easy: via formation of blocking antibodies”

A

Immediate Hypersensitivity

34
Q

Characteristic:(Relative ease of desensitization)

“Difficult: mechanism unknown”

A

Delayed Hypersensitivity

35
Q

Newer system which consists of four categories emphasizing the kind of immunopathological damage incurred.

A

Gell and Coombs Classification

36
Q

In Gell and Coombs Classification, What type are mainly immunoglobulin-mediated?

A

Type I,II,III

37
Q

In Gell and Coombs Classification, What Type is mediated by T cells and is synonymous with delayed hypersensitivity.

A

Type IV

38
Q

In Gell and Coombs Classification, What type is also called Immediate Hypersensitivity?

A

Type I

39
Q

In Gell and Coombs Classification, What type reaction ade initiated by the binding of antibody to a cell membrane or to the extracellular matrix.

A

Type II

40
Q

In Gell and Coombs Classification,What type hypersensitivity reaction involve the interaction of antibodies with soluble molecules to make soluble antigen-antibody complexes.

A

Type III

41
Q

In Gell and Coombs Classification, What type of hypersensitivity reaction are those in which cells of the immune system directly attack host cell in the absence of antibody.

A

Type IV

42
Q

What atopic reaction that is called anaphylaxis and affects the entire body?

A

systemic atopic response

43
Q

What Atopic reaction is the allergic symptoms depend on the anatomic location?

A

Local atopic reaction

IS (4 decks)

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