Hypersensitivity

Question 1

What is type I hypersensitivity? Give an example

Answer 1

IgE mediated. E.g. Allergy (anaphylaxis, asthma, eczema, hay fever)

Question 2

What is type II hypersensitivity? Give an example

Answer 2

Cytotoxic/Antibody mediated. E.g. goodpasture’s, hyperacute graft rejection,

Question 3

What is type III hypersensitivity? Give an example

Answer 3

Immune complex mediated E.g. extrinsic allergic alveolitis (farmer’s lung….ORGANIC), SLE, RA….

Question 4

What is type IV hypersensitivity? Give an example

Answer 4

Delayed type (cell-mediated). e.g. Chronic graft rejection, contact dermatitis, TB