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Hypertension Classes Flashcards

(85 cards)

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1
Q

metabolic pathway of lovastatin

A

P450 3A4 (CYP3A4)

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2
Q

class of furosemide

A

loop diuretics

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3
Q

metabolites in pitavastatin

A

no active metabolites

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4
Q

class of amlodipine

A

calcium channel blocker

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5
Q

class of eplerenone

A

potassium sparing diuretics

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6
Q

surface of atorvastatin

A

lipophilic

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7
Q

class of lovastatin

A

statin

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8
Q

metabolic pathway of rosuvastatin

A

CYP2C9

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9
Q

metabolites in pravastatin

A

no active metabolites, the major metabolites are produced by chemical degradation in the stomach rather than by cytochrome P450-dependent metabolism in the liver.

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10
Q

class of torsemide

A

loop diuretics

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11
Q

class of losartan

A

angiotensin II receptor blocker

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12
Q

class of prazosin

A

alpha adrenergic antagonist

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13
Q

metabolic pathway of pravastatin

A

renal metabolism

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14
Q

metabolite in simvastatin

A

active metabolite

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15
Q

class of metoprolol

A

beta blocker

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16
Q

class of valsartan

A

angiotensin II receptor blocker

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17
Q

surface of fluvastatin

A

lipophilic

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18
Q

class of hydrochlorothiazide

A

thiazide diuretic

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19
Q

class of penbutolol

A

beta blocker

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20
Q

class of sotalol

A

beta blocker

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21
Q

metabolite in fluvastatin

A

no active metabolites

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22
Q

metabolic pathway of simvastatin

A

P450 3A4 (CYP3A4)

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23
Q

metabolic pathway of fluvastatin

A

CYP2C9

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24
Q

class of vadlolol

A

beta blocker

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25
metabolism of losartan
cytochrome P450 (CYP) 3A4, 2C9 and 2C10 isoenzymes
26
surface of rosuvastatin
hydrophilic
27
class of simvastatin
statin
28
class of moexipril
ACE inhibitor
29
class of nisoldipine
calcium channel blocker
30
class of esmilol
beta blocker
31
class of felodipine
calcium channel blocker
32
class of enalapril
ACE inhibitor
33
surface of lovastatin
lipophilic
34
surface of pravastatin
hydrophilic
35
metabolites in atorvastatin
active metabolite
36
class of atenolol
beta blocker
37
class of quinapril
ACE inhibitor
38
class of perindopril
ACE inhibitor
39
class of olmesartan
angiotensin II receptor blocker
40
class of acebutolol
beta blocker
41
metabolic pathway of pitavastatin
little metabolism by CTP3A4
42
class of captopril
ACE inhibitor
43
class of candesartan
angiotensin II receptor blocker
44
common SE of amlodipine
lower extremity swelling
45
class of chlorthalidone
thiazide diuretic
46
class of lisinopril
ACE inhibitor
47
metabolic pathway of atorvastatin
P450 3A4 (CYP3A4)
48
class of rosuvastatin
stain
49
class of fluvastatin
statin
50
class of pitavastatin
statin
51
class of irbesartan
angiotensin II receptor blocker
52
class of spironolactone
potassium sparing diuretics
53
class of carvedilol
beta blocker
54
class of atorvastatin
statin
55
class of terazosin
alpha adrenergic antagonist
56
class of azilsartan
angiotensin II receptor blocker
57
class of nebivolol
beta blocker
58
class of propanolol
beta blocker
59
metabolites in rosuvastatin
minor active metabolite
60
class of verapamil
calcium channel blocker
61
class of nicardipine
calcium channel blocker
62
class of triamterene
potassium sparing diuretics
63
class of ramipril
ACE inhibitor
64
class of bisoprolol
beta blocker
65
class of telmisartan
angiotensin II receptor blocker
66
class of fosinopril
ACE inhibitor
67
class of labetolol
beta blocker
68
class of benazepril
ACE inhibitor
69
class of doxazosin
alpha adrenergic antagonist
70
class of pravastatin
statin
71
class of trandolapril
ACE inhibitor
72
class of nifedipine
calcium channel blocker
73
class of chlorothiazide
thiazide diuretic
74
class of amiloride
potassium sparing diuretics
75
surface of pitavastatin
lipophilic
76
class of diltiazem
calcium channel blocker
77
surface of simvastatin
lipophilic
78
metabolites in lovastatin
active metabolite
79
class of eprosartan
angiotensin II receptor blocker
80
class of bumetanide
loop diuretics
81
class of metolazone
thiazide diuretic
82
where does drug metabolism occur??
liver, intestinal wall, lungs, kidney, plasma
83
what is the main function of the liver with respect to drug metabolism?
enzymatically convert lipid soluble compounds to more water soluble compounds
84
mechanism of action of drug interactions with CYP metabolized drugs?
CYP related drugs inhibit or induce metabolism, affecting the metabolism of the other drugs (subtherapeutic or increased concentration of drug)
85
how could grapefruit be toxic for certain drugs?
inhibits CYP3A4, acts locally on small intestine and inhibits enterocyte CYP3A4, causing higher systemic levels of CYP3A4 active drugs

Pharmacology (5 decks)

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