Hyperthyroidism Flashcards
(23 cards)
Primary overet
TSH - low
T4 and T3 - high
Primary sub clinical
TSH - low
T4 and T3 - normal
Causes
Graves’ disease
Modular disease
Symptoms
Heat intolerance
Weight loss
Diarrhoea
Tachycardia
Tremor
Complications
AF
HF
Thyroid storm
Bulging eyes
Treatment options
Medication
Radioactive iodine
Surgery
1st line medication option
Crabmiazole
2nd
Propylthiouracil
What else can be used for tachycardia, tremor or anxiety
BB - propranolol
The thyroid drugs can cause agranulocytosis, what should patients look out for
Fever
Sore throat
Mouth ulcers
Bruising
How often should TSH levels be check in all anti thyroid drugs including levothyroxine
Every 6 weeks until TSH is within range, then every 3 months
What should women of childbearing age do whilst on carbimazole
Contraception
Which drugs can affect thyroid levels
Amiradone
Lithium
Why isn’t propylthioracil first line
Hepatotoxicity
- jauncdice
• abdominal pain
• dark urine
Graves’ disease
1st line management
Radioactice Iodine
What is the block and replace regimen
Fixed dose or combined carbimazole and levothyroxine
For how long
12-18 months
Which drug should be used in the first trimester of pregancy
Prophylthioracil
What should be used in the second and third
Carbimazole
DO NOT ISE IDOIDINE IN PREGNACY
What is thyrototoxicis
Too much throud
Signs
Diarroah
Weight loss
Fever
thyrototoxicis without hyperthyroidism management
Only supportive support
Beta blockers
