Hypothyroidism

Question 1

What happens in primary

Answer 1

Problem with the thyroid gland itself

Question 2

What happens in secondary

Answer 2

Problem with the pituitary gland

Question 3

Levels in primary overt

Answer 3

TSH - high
T3 and T4 - low

Question 4

Primary sub clinical

Answer 4

TSH - high
T3 and T4 - normal range

Question 5

Secondary

Answer 5

TSH - low
T3 and T4 - normal range

Question 6

Causes of primary

Answer 6

Iodine deficiency
Drugs - carbimazole
Autoimmune thyroiditis
Congenital

Question 7

Causes of secondary

Answer 7

Tumours - pituitary
Surgery
TSH deficiency
Drugs - cocaine

Question 8

Symptoms

Answer 8

Tired
Cold
Weight gain
Breathlessness
Hair thinning
Dry skin

Question 9

Complications

Answer 9

Goiter
LDL increase
Myxoedma

Question 10

1st line

Answer 10

Levothyroxine
Synthetic t4

Question 11

ADRs

Answer 11

Are like hyperthyroidism

Weight loss
Diarrhoea
Insomnia
Tremor
Palpitations

Question 12

How to administer levoyhtyroxine

Answer 12

In the morning 30 mins before food

Question 13

What does it interact with

Answer 13

Milk
Coffee
Grapefruit juice
Multivitamins

Question 14

Dose for under 65s

Answer 14

1.6mcrg / kg of body weight

Then round to 25mcrg

Question 15

Starting dose for 65>

Answer 15

25-50mg