I Clicker Questions

Question 1

Most drugs and neurotransmitters act upon

Answer 1

Membrane- bound receptors

Question 2

Ligand that have no effect on a receptor after binding are called

Answer 2

Antagonists

Question 3

While most _______ receptors are membrane bound, many ______ receptors are intracellular

Answer 3

Neurotransmitter; Hormone

Question 4

Both agonist and antagonists have ______ but only agonist have appreciable _______

Answer 4

Affinity; Efficacy

Question 5

Which of the following describes the interaction of two drugs when the combined drug effects are greater that would be predicted from that combination

Answer 5

Potentiation

Question 6

A regular drug user can have an elevated reaction to his usual drug if he takes that drug in a new environment. In this example the familiar environment in which the drug is normally taken in a:

Answer 6

Controlled Stimulus (CS)

Question 7

Drug users sometimes experience an elevated reaction to their drug when they take it in a new environment because the:

Answer 7

CR is not present to counteract the UR

Question 8

The key structural components of neurons are

Answer 8

Dendrites, axon, cell body

Question 9

The axon is the part of the neuron that

Answer 9

Transmits information to other neurons

Question 10

A synapse is

Answer 10

A gap that separates two different neurons

Question 11

The dendrites is the part of the neuron that:

Answer 11

Receives input from other neurons

Question 12

Action potentials occur in the

Answer 12

Axon

Question 13

Tolerance occurs as a result of cellular adaption to the presence of a specific drug

Answer 13

Pharmacodynamic

Question 14

The testing potential of a typical neuron is about _____

Answer 14

-70 mV

Question 15

The membrane potential at when action potential…..

Answer 15

Firing threshold

Question 16

The tendency for molecules to distribute themselves equally within a solution is Know as _____

Answer 16

Diffusion

Question 17

The tendency for molecules with the same signs (electrical charges) to move apart and molecules with opposite signs to move together is known as _______

Answer 17

Electrostatic pressure

Question 18

In a neuron at rest, the intracellular fluid has a high concentration of:

Answer 18

K+, a large number of negatively charged protein anions with small amounts of Na+

Question 19

Extracellular fluid around a neuron at rest has a high concentration of :

Answer 19

Na+ with small amounts of K+

Question 20

A transient depolarization of the postsynaptic membrane is know as:

Answer 20

Excitatory postsynaptic potential (EPSP)

Question 21

An excitatory post-synaptic potential (EPSP) is produced when neurotransmitter released from a pre-synaptic neuron binds to receptors on the posh synaptic neuron and :

Answer 21

Open neurotransmitter gated Na+ channels

Question 22

An inhibitory post synaptic potential (IPSP) is produced when neurotransmitter released from a pre synaptic neuron binds to receptors on the post synaptic neuron and _______

Answer 22

Open neurotransmitter gated Cl- or K+ channels

Question 23

After chronic use the need to administer more of a drug to achieve the same drug affect is known as

Answer 23

Tolerance

Question 24

After the drug administered has occurred :

Answer 24

Bioavailability

Question 25

The growth of dendritic spine serves to?

Answer 25

Increase surface area

Question 26

Blood absorbed into the blood stream

Answer 26

First pass

Question 27

Ionotropic

Answer 27

Charges ions

Question 28

The membrane potential at which action potential is triggered is known as

Answer 28

Firing threshold

Question 29

Synthesized in the cytoplasm of the soma in a process called

Answer 29

Translation

Question 30

Resting potentials =

Answer 30

Uneven distribution

Question 31

Voltage gated Na channels

Answer 31

Action potentials