I Clicker Questions Flashcards
(31 cards)
Most drugs and neurotransmitters act upon
Membrane- bound receptors
Ligand that have no effect on a receptor after binding are called
Antagonists
While most _______ receptors are membrane bound, many ______ receptors are intracellular
Neurotransmitter; Hormone
Both agonist and antagonists have ______ but only agonist have appreciable _______
Affinity; Efficacy
Which of the following describes the interaction of two drugs when the combined drug effects are greater that would be predicted from that combination
Potentiation
A regular drug user can have an elevated reaction to his usual drug if he takes that drug in a new environment. In this example the familiar environment in which the drug is normally taken in a:
Controlled Stimulus (CS)
Drug users sometimes experience an elevated reaction to their drug when they take it in a new environment because the:
CR is not present to counteract the UR
The key structural components of neurons are
Dendrites, axon, cell body
The axon is the part of the neuron that
Transmits information to other neurons
A synapse is
A gap that separates two different neurons
The dendrites is the part of the neuron that:
Receives input from other neurons
Action potentials occur in the
Axon
Tolerance occurs as a result of cellular adaption to the presence of a specific drug
Pharmacodynamic
The testing potential of a typical neuron is about _____
-70 mV
The membrane potential at when action potential…..
Firing threshold
The tendency for molecules to distribute themselves equally within a solution is Know as _____
Diffusion
The tendency for molecules with the same signs (electrical charges) to move apart and molecules with opposite signs to move together is known as _______
Electrostatic pressure
In a neuron at rest, the intracellular fluid has a high concentration of:
K+, a large number of negatively charged protein anions with small amounts of Na+
Extracellular fluid around a neuron at rest has a high concentration of :
Na+ with small amounts of K+
A transient depolarization of the postsynaptic membrane is know as:
Excitatory postsynaptic potential (EPSP)
An excitatory post-synaptic potential (EPSP) is produced when neurotransmitter released from a pre-synaptic neuron binds to receptors on the posh synaptic neuron and :
Open neurotransmitter gated Na+ channels
An inhibitory post synaptic potential (IPSP) is produced when neurotransmitter released from a pre synaptic neuron binds to receptors on the post synaptic neuron and _______
Open neurotransmitter gated Cl- or K+ channels
After chronic use the need to administer more of a drug to achieve the same drug affect is known as
Tolerance
After the drug administered has occurred :
Bioavailability
