Ibs, Celiac Flashcards

(35 cards)

1
Q

What is celiac disease

A

Malabsorptive disease in response to gluten

Small intestinal mucosa damage

Villous atrophy

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2
Q

Gluten found in _____

A

Wheat barley and rye

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3
Q

What is the problem with gluten what component.

A

Gliadin

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4
Q

Symptoms of celiac

A

Some asymptomatic or symptoms of malabsorption
- diarrhea
Weight loss
Weakness
Abdominal distention

In children, failure to thrive, delayed puberty

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5
Q

Celiac symptoms may relate to nutrition deficient

A

Iron deficiency anemia, fatigue, and pallor

Vit k deficiency, easy bruises
B12, neuropathy

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6
Q

Celiac disease skin manifestation

A

Dermatitis herpetiformis

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7
Q

What is dermatitis herpetiformis

A

Pruritis papulovesicles, over extensors, and extremities, trunk, scalp and neck

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8
Q

Dermatitis herpetiformis tx

A

Dapsone, lesion will respond to a gluten free diet, but response is slower, want to avoid a secondary skin infection

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9
Q

For celiac serology testing, patient is required to be on gluten for at least _____ weeks

A

6

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10
Q

Celiac disease gold standard test

A

Small intest8jal biopsy taken from distal duodenum shows villous atrophy

Celiac serology, but must not be on a gluten free diet to assess accurately

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11
Q

Tx for celiac

A

Strict elimination of gluten from diet

Dietician refer all,
Rice, corn and potatoes, are safe

Correct nutrition deficiency

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12
Q
A
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13
Q

What is ibs

A

Chronic functional disorder no organic caus e

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14
Q

Ibs characterized by

A

Abdominal pain and altered bowel habits

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15
Q

Ibs is characterized by reccurent abdominal pain at least 1 day a week in last 3 months and two or more of the following

A

Change in the frequency
Pain that related to defecation
Change in form of stool

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16
Q

Etiology and pathophys for Ibs

A

Usually involves underlying depression and anxiety
Can develop post gastroenteritis, or after viral or parasitic infection

Ask in social history, or ask any psychiatric hospitilizations

17
Q

Clinical feautures of Ibs

A

Intermittent and crampy pain in the lower abdomen

Diarrhea, frequent stools
Constipation, days to months

Red flag is being woken in the night to have a bowel movement

Constipation

18
Q

Ibs testing

A

Use Rome criteria.
CBC
Stool o and p, if recent travel

Colonoscopy is alarm Symptom, and family history colon cancer, over 45

19
Q

Alarm symptoms Ibs

A

Acute onset over 50
Blood in stool
Weight loss
Family history colon cancer

20
Q

Treatment for Ibs

A

Educate and support the patient

Reinforce chronic nature
Cope with symptoms
Lifestyle,
- exercise, sleep, avoid large meals, use fod maps

21
Q

Ibs pharmacotherapy aimed at pt with severe symptoms and o treating symptoms

A

Diarrhea, Imodium

Constipation, miralax , linzess

Psychotropic agent
, antidepressant

22
Q

Lactose intolerance is the inability to digest lactose due to shortage of _____

23
Q

Lactose intolerance affects what population

A

Native Americans, Asian Americans, African Americans

24
Q

Etiology for lactose intolerance

A

Acquired, and genetically regulated

Second to gi surgery or disease, such as chrons or celiac

25
Pathophys for lactose intolerance
Malabsorbed lactose is fermented and produces gas, increases stool load and result in diarrhea goes straight to large intestine, skips small intestine
26
Feature of lactose intolerance e
Bloat, gas, diarrhea, cramping
27
Red flag lactose intolerance
If patient is now losing weight need to evaluate further
28
Testing for lactose intolerance
Lactose free diet Hydrogenated breath test, given 50 gm lactose, positive test is a rise in breath hydrogen (>20 ppm within 90 mins)
29
Lactose intolerance treatment
Make patient comfortable Lactose free diet Use lactaid, milk ensyme replacement Calcium and vitamin d supplement
30
What is polyp
Clump of cells, in the colon, stalk like
31
Risk for polyps,
Diet high with red meat Low fiber Obesity Men greatest risk
32
Can u distinguish between hyperplasticity polyp, and adenomatous polyp
No must biopsy
33
Hyperplastic polyp what are they
Small, in rectum or sigmoid Less than 5 mm No malignancy potential
34
Adenomatous polyp
2/3 are this kind Some cancer potential Larger the lesion the more likely the risk for cancer, >1 cm
35
Best way to visualize polyps
Colonoscopy, And polypectomy