Identification Flashcards Preview

MALIGNANT HEME > Identification > Flashcards

Flashcards in Identification Deck (23):
1

Q image thumb

Hemophagocytosis

2

Q image thumb

Dutcher Body- PAS positive stain appears intranuclear, actually cytoplasmic and invaginates nucleus in Waldenstroms and Myeloma

3

Q image thumb

Bone Marrow Fibrosis

4

Q image thumb

Pappenheimer Body- siderotic granule made of iron, often in clusters. Assoc. with splenectomy, hemolytic anemia, sideroblastic anemia, megaloblastic anemia, and hemoglobinopathies

5

Q image thumb

Mott Cell- seen in Myeloma

6

Q image thumb

Dohle Body

7

Q image thumb

Dohle Body​

8

Q image thumb

Mott Cell (Grape Cell) seen in Myeloma

9

Q image thumb

Hemophagocytosis

10

Q image thumb

Flame Cell- Eosinophilc appearing plasma cell in Multiple Myeloma often in IgA secreting myeloma

11

Q image thumb

Large Granular Lymphocyte- larger than resting lymphocyte w/ more cytoplasm and azurophilic granules. Either CD8 T cells or NK cells (CD56) and seen in viral infections and large granular lymphocytic leukemia

12

Q image thumb

Chediak-Higashi Syndrome. AR disorder of abnormal lysosome trafficking leading to inclusions in leukocytes. Recurrent infections, partial albinism, and peripheral neuropathy​

13

Q image thumb

Idiopathic Hypereosinophilic Syndrome with BM showing expansion of mature eosinophils and eosinophilic myelocytes

14

Q image thumb

Flame Cell. Plasma cells with distinctive pinkish hue thought to be precipitated immunoglobulin most likely IgA. Seen in Myeloma. 

15

Q image thumb

Microangiopathic Hemolytic Anemia. Note the schistocytes

16

Q image thumb

Hemophagocytic Lymphohistiocytosis- the histiocyte nuclei are the more spongy ones. They are engulfing lymphoma cells.

17

Q image thumb

Pseudothrombocytopenia- platelet clumping due to interaction of EDTA with Gp IIb/IIIa

18

Q image thumb

Follicular Lymphoma- note the paratrabecular lymphoid aggregates

19

Q image thumb

Smudge Cells of CLL

20

Q image thumb

Cold Agglutinin Disease- often IgM or anti-C3 ​

Recall: most hemolysis takes place in liver whereas warm AIHA takes place in spleen. Can be assoc. with Mycoplasma

21

Q image thumb

Plasma Cells, likely Myeloma containing Snapper-Schneid granules​

22

Q image thumb

Dutcher Body- PAS + staining intranuclear inclusion 

23

Q image thumb

Pelger Huet Anomaly- bilobed neutrophil. If present in only some neuts it is pseudo-Pelger-Huet anomaly and indicative of MDS (dysmyelopoiesis)