IDS Flashcards

1
Q

organisms which cause diarrhea via pre-formed toxins (3)

A
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2
Q

organisms which cause diarrhea via cytotoxins (2)

A
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2
Q

organisms which cause diarrhea via entero toxins (4)

A
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3
Q

The most clinically important flaviviruses that cause the fever and myalgia syndrome are

A

Dengue viruses causing breakbone fever

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4
Q

Most important of the parasitic diseases of humans,

A

Malaria

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5
Q

organisms causing filariasis (2)

A
  • Wuchereria bancrofti
  • Brugia malayi
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6
Q

malaria species with Malignant vs Benign Tertian periodicity

A
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7
Q

malarial species with banana-shaped gametocytes

A
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8
Q

malaria species with preference to:
* young
* old
* both young and old

A
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9
Q

malarial species with band or rectangular forms of trophozoites

A
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10
Q

malarial species with irregularly shaped large rings and trophozoites; Schuffner dots

A
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11
Q

malarial species with enlarged and oval with tufted ends Schuffner dots

A
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12
Q

malarial species associated with cerebral malaria

A

P. falciparum

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13
Q

malarial species with tendecny to relapse

A

P. vivax
P. ovale

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14
Q

relapse in malaria is due to reactivation of what malaria stage

A

hypnozoites

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15
Q

When a patient in or from a malarious area presents with fever, what should be done to confirm diagnosis and identify species of infecting organism?

A

Thick and thin blood smears

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15
Q

What is blackwater fever?

A

Acute hemolytic anemia with massive hemoglobinuria in malaria

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16
Q

Highest endemicity of malaria in

A

(MIMAROPA region) Palawan

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17
Q

Hallmark features of enteric fever

A
  • Fever and abdominal pain

Enteric fever is a misnomer in that hallmark features are variable

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18
Q

rose spots or faint, salmon-colored, blanching, maculopapular rashes located primarily on the trunk and chest are found in what disease

A

enteric fever

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18
Q

Term for the neuropsychiatric symptoms with picking at bedclothes or imaginary objects in patients with enteric fever

A

Muttering delirium or coma vigil

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19
Q

Risk factors for chronic carriage in patients with

A
  • Women
  • infants,
  • persons who have biliary abnormalities or concurrent bladder infection with Schistosoma haematobium
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20
Q

Most effective class of agents in treatment in enteric fever

A

fluoroquinolones

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21
Q

Most severe form of leptospirosis

A

Weil’s Syndrome ( characterized by jaundice, renal dysfunction, and hemorrhagic diathesis)

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22
Severe leptospirosis should be treated with what medication
IV Penicillin
23
Prophylaxis for leptospirosis exposure
Doxycycline
24
Differentiate the ff in terms of mode of transmission : *Schistosoma japonicum * Paragonimus westermani * Clonorchis sinensis
25
Differentiate the ff in terms of body part affected : *Schistosoma japonicum * Paragonimus westermani * Clonorchis sinensis
26
Differentiate the ff in terms of mode of intermediate hosts : *Schistosoma japonicum * Paragonimus westermani * Clonorchis sinensis
27
Differentiate the ff in terms of drug of choice : *Schistosoma japonicum * Paragonimus westermani * Clonorchis sinensis
28
Intermediate host of S.japonicum
Oncomelania quadrasi (snail)
29
Intermediate host of P. westermani
Sundathelphusa philippina (mountain crab)
30
Symptomatic acute schistosomiasis usually seen in travelers who have contracted the infection (schistosomiasis) for the first time
Katayama fever
31
schistosomiasis is most prevalent in what province
Oriental Mindoro
32
Mainstay in tbe control program of schistosomiasis in the Philippines
Mass treatment with praziquantel
33
Clostridium tetani are anaerobic, gram negative, spore-forming rods | True or False
False gram POSITIVE dapat
34
Most characteristic pathologic finding in rabies
Negri bodies
35
term for the eosinophilic cytoplasmic neurons that are composed and viral RNA in rabies
Negri bodies
36
Examples of bacteriostatic antibiotics (6)
37
Examples of bactericidal antibiotics (6)
38
Example of 1st gen cephalosporin (1)
39
Example of 2nd gen cephalosporin (2)
40
Example of 4th gen cephalosporin (1)
41
Example of 3rd gen cephalosporin (4)
42
Example of 5th gen cephalosporin (1)
43
Protein synthesis inhibitor that causes gray baby syndrome
44
Protein synthesis inhibitor that causes tooth enamel discoloration
44
only Protein synthesis inhibitor that binds to 30S subunit
45
Protein synthesis inhibitor that causes pseudomembranous colitis
clindamycin
46
aminoglycoside that is absolutely contraindicated in myasthenia gravis due to its side effect (neuromuscular blockade)
gentamicin
47
aminoglycoside that has pseudomonal coverage and has narrow therapeutic window
47
aminoglycoside used for treatment of drug-resistant gonorrhea
48
aminoglycoside used for treatment of hepatic encephalopathy (2nd line)
neomycin
49
FQ that causes tendonitis or tendon rupture in people > 60 y/o and in patients taking prednisone
50
Example of 2nd, 3rd, vs 4th gen cephalosporin
51
FQ used for UTI and GIT infections
52
FQ used for pulmo infections
52
FQ used for ocular infections
53
most hepatotoxic TB meds
54
TB med that causes peripheral neurotoxicity
55
anong klaseng color-blindness ang dinudulot ng ethambutol
red-green color blindness
56
top 3 hepatotoxic anti TB meds
pyrazinamide rifampicin isoniazid
57
leprosy drug that causes methemoglobinemia and hemolysis if px is G6PD deficient
Dapsone
58
leprosy drug that causes red-orange urine
59
leprosy drug that causes red-black discoloration that accumulates esp in lesional areas
Clofazimine
60
antibiotic used to treat pseudomembranous colitis
metronidazole
61
antibiotic which cause disulfiram-like reaction when taken with alcohol
metronidazole
62
Nitrofurantoin causes this pulmonary complication
pulmonary fibrosis
63
antifungal used as topical treatment for dermatophytosis and candidiasis
Ketoconazole
64
antifungal that causes gynecomastia as side effect
64
antifungal used for prophylaxis and treatment of candidiasis and cryptococcosis
65
acyclovir is used to treat what 2 viruses
65
antiviral that causes obstructive crystalline nephropathy and AKI if not adequately hydrated
66
ganciclovir is used to treat what virus (1)
67
Foscarnet is used to treat what 3 viruses
68
antiviral which causes cerebellar dysfunction and livedo reticularis
Amantadine
69
antiviral that is used as treatment and prevention of influenza A and B
70
antiviral used as treatment of hepatitis B infection and HIV
Lamivudine
71
antiviral used as treatment of hepatitis C and RSV infection
Ribavirin
72
examples of NNRTI (3)
73
anti malarial drug that causes retinopathy
74
anti malarial drug that causes cinchonism
quinine
74
anti malarial drug that should not be given in pregnant patients
Primaquine
75
anti malarial drug that is the DOC for eradication of hypnozoites of P. vivax and ovale to eradicate persistent liver stages and prevent relapse
Primaquine
76
Only anti malarial drug advised for pregnant women traveling to areas with drug-resistant malaria
Mefloquine
77
anti malarial drug that is generally considered safe in the second and third trimesters of pregnancy
Mefloquine
78
anti malarial drug used as prophylaxis in areas with chloroquine- or mefloquine-resistant P.falciparum
Doxycycline
79
Drug of choice for all patients with severe malaria everywhere
Artesunate
80
Should be used in pregnant women with severe malaria
81
* DOC for asymptomatic cyst carriers of E. histolytica * Luminally active agent used to eradicate the cysts of£. histolytica
82
DOC for Cryptosporidium parvum infection
82
DOC for * Amoebic dysentery * Trichomoniasis * Giardiasis
83
DOC for Pneumocystis jirovecii pneumonia
84
DOC for Toxoplasmosis
85
DOC for African sleeping sickness
86
DOC for Chagas disease
87
DOC for Leishmaniasis
88
anti-helminthic drugs which inhibit helminthic microtubules (2)
albendazole, mebendazole
89
Treatment for echinococcosis, intestinal parasitic nematodes
albendazole
90
Drug of choice for filarial disease and Loa loa
DEC
91
Considered more effective than albendazole for Strongyloides
92
First line agent for onchocerciasis
93
Side effect of this anti-helminthic drug is Mazzotti reaction
94
Used in Enterobius infection
95
Drug of choice for trematodes and cestodes; EXCEPT echinococcosis (because it is treated with albendazole)
96
Back-up drug to Praziquantel