IJOMI_102122022_ZZChen

Question 1

OSU article : Ti as a modifier of inflammation around implants

Answer 1

Aim:

• Analyze peri-implant crevicular fluid for presence and level of dissolved titanium
• Evaluate association of titanium levels with peri-implant disease status, clinical inflammation severity, and inflammatory mediators

Similar titanium levels in peri-implant and sulcular crevicular fluids:
NSSD in titanium levels for peri-implant disease diagnoses
NSSD in titanium levels for clinical inflammation severity levels

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Titanium can be detected in crevicular fluid of implant site and of adjacent tooth
Titanium concentration was not related to peri-implant disease diagnosis, or clinical inflammation severity
But, titanium concentration was associated with increased concentrations of inflammatory mediators (in particularly IL-4)