immmunity overview

Question 1

classification of immune deficiencies

Answer 1

resulting from genetic or developmental effect
present from birth
may not be clinically observes until later in life

2’
result of malnutrition, cancer, drug treatment etc. e.g AIDS

Question 2

give some of the 10 warning signs for primary immune def

Answer 2

Question 3

what is pollen immunotherapy or cat immunotherapy

Answer 3

regular application of whatever the allergen is

subcut injection (pre-seasonal injections (6 injections, 4 at weekly, last 2 at 2 weekly) 3 years)- pollen grass mix, pollinex treees, alutard

oral/sublingual route (daily, 3 years)- stallergenes, oralcan, grazax

Question 4

what are storgae proteins and oral allergy syndrome

Answer 4

the major allergenic proteins- resulting in systemic effects rather than local effects

oral allergy syndrome is a localised reaction that is not systemic. IgE cross reactivity phenomanen- all plant based foods will contain simalar proteins to tree grass and weeds, immune system might not recognise the subtle differences, and react to food but it actually doesnt like hayfever.

the ability to tolerate well cooked foods shows that this is likely diagnosis

Question 5

replication cycle of HIV

Answer 5

Question 6

why was the polio vacciene not great initally

Answer 6

they gave 3 strains in one
but if type 2 is admin with 1 and 3 there are reactions

it can mutate back to a virulent form and cause disease

Question 7

what are sub unit vaccienes

Answer 7

antigen that is immunogenic.

Question 8

what is an adjuvent

Answer 8

something that helps the vaccinene to be seen by the immune system.

can trap antigens in and slowly release them over time, making it longer