IMMUMO- 3 Part 2 Flashcards Preview

IMMUNO EXAM 3 > IMMUMO- 3 Part 2 > Flashcards

Flashcards in IMMUMO- 3 Part 2 Deck (32):
1

FasL-fas interaction results in pro-caspase 4 by FADD

False because should say 8 NOT 4

2

NK cells make up 30% of circulation lymphocytes

False because it should say (5-10%)

3

Viral load is reduced as soon as NK proliferation occurs

True ???????

4

CD2 is an activating receptor on NK cells

True ( also, CD16, Nkp30, NKR-PLL)

5

The CD94/NKG2 heterodimer recognizes HLA-A

false (b/c should have said HLA-E instead)

6

The cell type responsible for elevation of IFN-a and IFN-B soon after a viral infection is the

Myeloid DC ???????
(don't know what is PDC's)

7

The cytokine secreted by macrophages that is responsible for indicating Th cells towards a Th1 phenotype is

IL-12

8

Release of perforin and granzyme at the junction between a target cell and a cytotoxic cell requires

calcium

9

Granzyme B induce apoptosis thru

mitochondrial attack resulting in release of cytochrome-C ????????

10

Virus tiers start decreasing after levels of

IFN-y and IFN-b rise ??????

11

NK cells who have been involved in cell mediated killing

?????????

12

NK cells recognize target cells then

???????

13

The CD94/ NKG2 receptor recognizes

NONE of the Above (correct answer would be HLA-E)

14

Which of the following mediators are not used in cell mediated cytotoxicity?

IL-10

15

Which of the following cell types does not utilize ADCC(antibody dependent cell cytotoxicity)

Tc

16

Which of the following is true about fatty acids?

All of the above

17

Which of the following fatty acids is an omega 3?

Docosahexarnoic acid (w-3) DHA

18

Which of the following fatty acids is an omega 4?

???????

19

In blood fatty acids

All of the above

20

Which of the following is a mechanism via which fatty acids will decrease inflammation?

None of the above
(IL-6, IL-12, IL-23)

21

Phospholipids nucleotides are comprise of

None of the above ??????

22

Hydrogenation of oils

Increases carbon-carbon doubles bonds of fatty acids

23

Phosphatidylserine

is a recognition marker for apoptotic cells

24

Phosphatidylserine

All of the above

25

Which protein has high affinity for phosphatidylserine

annexin V

26

Which organ is DHA most prevalent as part of phosphotidylserine.

Brain

27

Which of the following is true about arachidonic acid?

It is an omega 6 ??????

28

Non-steroidal-anti-inflammatory (NSAIDs) such as ibuprofen and aspirin inhibit?

COX enzymes

29

Baby formula is fortified with which fatty acids

A and B (DHA and ARA)

30

Oil hydrogenation involves

All of the above

31

DHA has been shown to have the following effect on IxBa upon LPS stimulation

decrease its stability

32

Which of the following is true about Nk-kb nuclear translocation

??????? (reduced something))))