Immune defficiency

Question 1

Whats worse defect inWHat B cells or T cells?

Answer 1

T cells - T helper cells

Question 2

What type of infections are you more at risk of if you havr C8 deficiency?

Answer 2

Neisseria

Question 3

what does SCID stand for

Answer 3

Severve combined immunodefficiency syndrome

Question 4

Results of SCID?

Answer 4

NO IgA, low IgM
Reduced T and NK cells
Die unless bone transplant

Question 5

Treatment for SCID?

Answer 5

Bone marrow transplant

Question 6

Name a B cell defienceny?

Answer 6

X linked agammaglobulinaemia (absent mature B cells)

Question 7

Chronic Granulomatous disease pathology?

Answer 7

Neutrophils pumping out mediators. (Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease (PIDD) which increases the body’s susceptibility to infections caused by certain bacteria and fungi. Granulomas are masses of immune cells that form at sites of infection or inflammation)

Question 8

What is a primary genetic cause of immunodeficiency?

Answer 8

IRAK-4 deficiency is an inherited disorder of the immune system (primary immunodeficiency). This immunodeficiency leads to recurrent infections

Question 9

What enzyme is key in phagocytosis?

Answer 9

NADPH oxidase - allows H+ plus to enter cells and activate the enzymes