Immune/HIV Flashcards
(33 cards)
stimulates immune response
Antigen
Protein that is produced in response to antigen
Antibody
Present @ birth; first line of defense
Innate native immunity
Local manifestations of inflammatory response
Redness heat pain swelling loss of function
If WBC less than 5,000
leukopenia
More than 11,000
leukocytosis
systemic inflammatory response
Increased WBC "shift to the left" Malaise Nausea/anorexia Increased pulse & RR Fever
when the person is exposed to a live pathogen, develops the disease, and becomes immune as a result of the primary immune response
natural active immunity
can be induced by a vaccine, a substance that contains the antigen
artificial active immunity
mother to fetus
natural passive immunity
short term immunization by injection of antibodies, such as gamma globulins, that are not produced by the recipient’s cell; immediate protection
Artificially passive immunity
HIV can occur during
pregnancy
Immune problems start when CD4+ T-cell counts drop
<500 cells
Severe problems develop when
<200 CD4+ T cells
Normal cell ranges
800-1200
Acute infection
mono like symptoms 2-4weeks after infection Fever Swollen lymph nodes sore throat headache malaise nausea HIGHLY INFECTIOUS
the interval between untreated HIV infection and a diagnosis of AIDS.
Asymptomatic infection
Symptomatic infection the CD4 cells decline closer to
200 cells
Symptoms become worse
Symptomatic infection
Shingles
Persistent vaginial candida infection
Herpes
Bacterial infections
Diagnostics for HIV
ELISA & Western Blot
then test viral load
AIDs is characterized by:
Severe immune system suppression and CD4+ T-cell counts < 200 cells/μL
•An opportunistic infection
The most useful screening tests for HIV are those that detect
HIV specific antibodies
CD4 normal range
800-1200
Abnormal blood tests can be caused by
decreased WBC–especially lymphopenia & neutropenia
Low platelet counts
Anemia