Immune mediated disease (tolerance & autoimmunity)

Question 1

Immune Deficiency Diseases

Question 2

Recognise the need for balance in immune response

Question 3

Describe the consequence of too great or too small immune response

Question 4

Explain how tolerance for self-antigens is generated
a. Mechanism of self-tolerance

Question 5

Describe how/why self-antigens can become a target for host immune response and cause disease
a. The contribution of genetic and environmental factors
b. The existence of emerging factors

Question 6

How loss of self-tolerance causes disease
a. Recognise the types of diseases that arise as a results of autoimmunity
b. Describe how autoimmunity contributes to the pathogenesis and pathology of specific diseases

Question 7

Explain how the immune system contributes to graft rejection

Question 8

Describe the possible causes of hypersensitivity and the mechanism by which it causes diseases

Question 9

Explain the cause and consequences of too little immunity