Immune pathology Of Mycetoma Flashcards
(24 cards)
What is Mycetoma?
Mycetoma is a chronic granulomatous inflammatory disease.
What is the most common causative agent of eumycetoma?
Madurella mycetomatis is the most common causative agent of eumycetoma.
True or False: Mycetoma is more prevalent in males than females.
True
What type of immune response is typically seen in mycetoma?
A T-cell mediated immune response.
What is the hallmark of mycetoma pathology?
Granuloma formation.
Which cytokine is typically elevated in mycetoma?
Interferon-gamma (IFN-gamma).
Fill in the blank: Mycetoma is characterized by the formation of __________.
Sinuses.
What type of immune cells are found in high numbers in mycetoma lesions?
Macrophages and lymphocytes.
True or False: Mycetoma lesions typically have a high fungal burden.
True
What is the treatment of choice for eumycetoma?
Prolonged antifungal therapy.
What is the most common site of mycetoma infection?
The foot.
What is the main goal of mycetoma treatment?
To eradicate the infection and prevent recurrence.
True or False: Mycetoma is a contagious disease.
False
What is the role of surgery in mycetoma management?
To remove non-viable tissue and promote healing.
Fill in the blank: Mycetoma is classified as a __________ infection.
Subcutaneous.
What is the preferred imaging modality for evaluating mycetoma lesions?
Magnetic Resonance Imaging (MRI).
True or False: Mycetoma can lead to severe deformities if left untreated.
True
What is the primary method of mycetoma diagnosis?
Clinical examination and microbiological culture.
What is the role of histopathology in mycetoma diagnosis?
To confirm the presence of granulomas and identify the causative agent.
True or False: Mycetoma is a self-limiting disease.
False
What is the main challenge in mycetoma treatment?
The high rate of treatment failure and recurrence.
Fill in the blank: Mycetoma is commonly seen in __________ regions.
Endemic.
What is the significance of the immune response in mycetoma?
It plays a crucial role in disease pathogenesis and treatment outcomes.
True or False: Mycetoma can affect multiple body sites simultaneously.
True
