Immune System Flashcards

1
Q

1 lymphoid tissues

A

thymus gland and bone marrow

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2
Q

2 lymphoid tissues

A

encapsulated- spleen and lymphoids

unencapsulated

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3
Q

encapsulated

A

spleen-removes damaged red blood cells (phagocytosis)

lymphodes- contains immune cells to trap pathogens

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4
Q

unendcapsulated

A

collections of immune cells in various tissues

includes tonsils, gut associated lymphoid tissues, peyers patches

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5
Q

immune system functions

A

protection from pathogens
removal of dead or damaged tissue
recognition and removal abnormal cells

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6
Q

microbes

A

include bacteria, viruses, fungi, one celled protozoans

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7
Q

foreign substances

A

molecules or cells not of the body potentially can elicit an immune response

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8
Q

innate immunity

A

present before pathogenic invasion, effective before birth; non specific
recognition of traits shared by broad ranges of pathogens using a small set of receptors
rapid resonse

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9
Q

adaptive immunity

A

responds after exposure to pathogen, very specific to pathogen

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10
Q

adaptive immunity

A

recognition of traits specific to particular pathogens, using a vast array of receptors
slower response
vertebrates only

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11
Q

2 phagocytosis cells

A

macrophages

neutrophils

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12
Q

macrophages

A

scavenger of tissues
remove larger particles
most phagocytic

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13
Q

antigen

A

compound that activities immune response

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14
Q

neutrophils

A

most abundant white blood cells

release a number of cytokines, involved in inflammatory response.

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15
Q

internal defences

A
phagocytosis
fever production
antimicrobrial proteins
inflammatory response
natural killer cells
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16
Q

antimicrobrial proteins

A

directly attack pathogens or interfere with their reproduction

17
Q

inflammatory response

A

increase temp, attraction of white blood cells and swelling associated with tissue injury or pathogenic infection

18
Q

histamine

A

released from mast cells and basophils
increased white blood cells to injury site
opens pores in capillaries
dilates blood vessels increasing blood flow to region

19
Q

antihistamines

A

prevent mast cell degranulation or block histamine receptors

20
Q

cytokines

A

molecules released from one cell that effect the growth or activity of another cell
attract other immune cells to site
induce fever

21
Q

natural killer cells

A

attack virus cells by recognizing certain protein signatures on these cells and triggering apotosis
release perforins ( pore forming proteins)
granzymes (proteases)

22
Q

acquired immune response

A

the body recognizes specific foreign substance and selectively reacts to it

23
Q

B lymphocytes

A

formed in bone marrow
provide primary and secondary antibody responses
primarily secrete antibodies
recognize intact antigens

24
Q

T lymphocytes

A

derived from lymphocytes that have migrated to the thymus gland form the bone marrow
participate in cell mediated immunity
recognize small fragments of antigens bound to MHC molecules

25
Q

MHC

A

major histocompatability complex

26
Q

clonal expansion

A

selective proliferation and differentiation of lymphocytes that occurs the first time the body is exposed to a particular antigen

27
Q

passive immunity

A

when a person is given antibodies made by another organism

antivenoms

28
Q

anit venoms

A

pre made antibodies against toxin

29
Q

immunization(vaccination)

A

injection of non-pathogenic components of a pathogen in order to mound a secondary response later

30
Q

MAC: membrane attack complex

A

a series of 5 complement proteins form a pore in the membrane causing a loss of ion distributions

31
Q

allergy

A

inflammatory immune system response to a nonpathogenic antigen

32
Q

anaphylactic shock

A

massive constriction in bronchioles
dilation of peripheral vessels
drop in blood pressure

33
Q

self tolerance

A

lack of response of lymphocytes to cells of the body

34
Q

autoimmune diseases

A

body makes antibodies against own cells

through t cell activated b lymphocytes