Immune thrombocytopenic pupura (ITP) Flashcards Preview

Long Case - Haematology > Immune thrombocytopenic pupura (ITP) > Flashcards

Flashcards in Immune thrombocytopenic pupura (ITP) Deck (4)
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1

WTF is it?

Anti-platelet antibodies

2

Presentation

Acute - children, 2 weeks after viral infection with sudden self-limiting purpura
Chronic - (mainly women), fluctuating course: bleeding, purpura (pressure areas), epistaxis, menorrhagia. NO splenomegaly

3

Ix

Bloods: increased megakaryocytes in marrow, anti-platelet Ab

4

Management

Meds:
- None if mild
- Prednisone 1mg/kg/d if plt < 20
- Splenectomy cures 80% if relapses
- immunosuppression: azathioprine, cyclophosphamide

Other:
platelet transfusion (only for life threatening bleed or splenectomy as pt destroys them so fast)
IVIg may temporarily raise Plts