Flashcards in Immunity Deck (20):
Innate (non-specific immunity)
External physical barriers or chemical barriers by the skin a mucous membranes.
Includes: antimicrobial substances, killer cells, phagocytes, inflammation and fever
The ability of the body to defend itself against specific invading agents such as bacteria, toxins, viruses and foreign tissues.
Recognized as foreign and provoke an immune response
Where do B-Cells develop?
In the red bone marrow. Mature there throughout life.
Where do t-cells develop?
In the red bone marrow, but mature in the thymus. Hence, *T* cells.
Cell Mediated immunity
Cytotoxic T-cells kill invading antiges directly
B-cells transform into plasma cells, which synthesize and secrete specific proteins called ANTIBODIES or IMMUNOGLOBINS
The ability to carry out adaptive immune responses
The ability of the immune system to distinguish self from non-self.
WBCs of Innate immunity
Function of Neutrophils
Phagocytic. Secrete lysozome (antibacterial)
Function of Eosinophils
Phagocytic. Control inflammatory response and anti-parasitic actions.
Function of Basophils
NOT phagocytic. Engages in inflammatory response.
Adaptive immunity cells
Function of Lymphocytes
B-Cells: Produce antibodies (as plasma cells)
T-Cells: Recognize and kill foreign cells
Function of monocytes
Precursor to macrophages
Kills infected or altered host cell
Stimulates activation of B-cells and T-cells
Activates into memory B cells or plasma cells