Immuno MedGems

Question 1

Other than T lymphocytes, what cell type is primarily infected by HIV?

Answer 1

Macrophages

Question 2

Which infection should be ruled out before starting infliximab?

Answer 2

TB

Infliximab = anti-TNF alpha

Anti-TNF alpha associated with the activation and dissemination of latent TB

Question 3

What type of vaccine is comprised of a polysaccharide bound to a immunogenic toxin?

Answer 3

Conjugate

Question 4

What antigen is injected intradermally as part of the mantoux screening test for tuberculosis?

Answer 4

Tuberculin purified protein derivative

Question 5

What is the main metabolite of azathiroprine?

Answer 5

6-Mercaptopurine

Question 6

First line treatment of febrile non-haemolytic transfusion reaction

Answer 6

Paracetamol

Question 7

What class of medication acts by inhibiting phospholipase A2 and reduces the expression of pro-inflammatory cytokines?

Answer 7

Corticosteroids

Question 8

What antiretroviral drug is given as IV monotherapy during labour to prevent vertical transmission of HIV-1?

Answer 8

Zidovudine

Question 9

What should HAART for HIV be comprised of?

Answer 9

Two nucleotide reverse transcriptase inhibitors (NRTIs) and another class of drug

Question 10

Which subtype of T helper cells are implicated in the development of allergic diseases, such as asthma or eczema

Answer 10

T helper 2 cells