IMMUNOGLOBULINS- INTERPRETATION

Question 1

Greatest concentration in serum

Answer 1

IgG

Question 2

Has 4 subclasses:

Answer 2

IgG

Question 3

Activates complement

Answer 3

IgG

Question 4

Crosses placenta

Answer 4

IgG

Question 5

IgG has ____% of total antibody concentration

Answer 5

75%

Question 6

Largest antibody (pentamer)

Answer 6

IgM

Question 7

Fixes complement best (multiple binding sites)

Answer 7

IgM

Question 8

Prominent in early immune response (indicates acute infection)

Answer 8

IgM

Question 9

IgM has ___% of total antibody concentration

Answer 9

5-10%

Question 10

Predominant antibody in body secretions (tears, saliva, nasal mucosa)

Answer 10

IgA

Question 11

Serum IgA:

Answer 11

MONOMER

Question 12

Secretory IgA

Answer 12

DIMER

Question 13

Primary defense against local infections at mucosal surface:

Answer 13

IgA

Question 14

Two subclasses

Answer 14

IgA

Question 15

Unknown function

Answer 15

IgD

Question 16

Present on B cell surface

Answer 16

IgD

Question 17

Allergy
Type I hypersensitivity

Answer 17

IgE

Question 18

Involved in release of histamines from mast cells.

Answer 18

IgE

Question 19

Greatest plasma concentration , Approximately 70%, Goes across Placenta

Answer 19

IgG

Question 20

Largest immunoglobulin molecule, Activates Complement

Answer 20

IgM

Question 21

Captures IgM antibodies (early response to infection)

Answer 21

IgM Line

Question 22

Captures IgG antibodies (later response, indicating immunity or past infection)

Answer 22

IgG Line

Question 23

Ensures that the test is valid by detecting the movement of reagents along the strip

Answer 23

Control Line (C)

Question 24

Control Line (C): Visible
IgM Line: Absent
IgG Line: Absent

RESULT-
INTERPRET-

Answer 24

RESULT- NEGATIVE
INTERPRET- The Patient is NOT INFECTED

Question 25

Control Line (C): Visible IgM Line: Visible IgG Line: Absent RESULT- INTERPRET-

Answer 25

RESULT- POSITIVE FOR IgM only INTERPRET- The patient is in the EARLY STAGE of exposure

Question 26

Control Line (C): Visible IgM Line: Absent IgG Line: Visible RESULT- INTERPRET

Answer 26

RESULT- POSTIVE FOR IgG only INTERPRET- The patient had a PREVIOUS infection or HAS BEEN VACCINATED

Question 27

Control Line (C): Visible IgM Line: Visible IgG Line: Visible RESULT- INTERPRET

Answer 27

RESULT- POSTIVE BOTH IgG and IgM INTERPRET- The patient may be in ACTIVE PHASE of infection

Question 28

Control Line (C): Absent IgM Line: Absent or Visible IgG Line: Absent or Visible

Answer 28

RESULT- INVALID INTERPRET- The test is INVALID

Question 29

The test is invalid (can be) due to:

Answer 29

1. Insufficient sample volume. 2. Improper procedure or defective kit.

Question 30

has previous infection

Answer 30

IgG

Question 31

currently have infection

Answer 31

IgM